Shift in bacterial etiology from the CAPNETZ cohort in patients with community-acquired pneumonia: data over more than a decade

被引:15
作者
Braeken, D. C. W. [1 ]
Essig, A. [2 ]
Panning, M. [3 ]
Hoerster, R. [4 ]
Nawrocki, M. [5 ]
Dalhoff, K. [4 ]
Suttorp, N. [5 ,6 ,7 ]
Welte, T. [5 ,8 ,9 ,10 ]
Pletz, M. W. [5 ,11 ]
Witzenrath, M. [5 ,6 ,7 ]
Rohde, G. G. U. [5 ,10 ,12 ]
Rupp, J. [5 ,13 ]
机构
[1] Maastricht Univ Med Ctr MUMC, Dept Resp Med, Maastricht, Netherlands
[2] Univ Hosp Ulm, Inst Med Microbiol & Hyg, Ulm, Germany
[3] Univ Freiburg, Univ Med Ctr, Inst Virol, Freiburg, Germany
[4] Univ Hosp Schleswig Holstein, Pulmonol, Med Clin 3, Lubeck, Germany
[5] CAPNETZ STIFTUNG, Hannover, Germany
[6] Charite Univ Med Berlin, Dept Infect Dis & Pulm Med, Berlin, Germany
[7] Charite Univ Med Berlin, Div Pulm Inflammat, Berlin, Germany
[8] Hannover Med Sch, Dept Pneumol, Hannover, Germany
[9] Hannover Med Sch, German Ctr Lung Res DZL, Hannover, Germany
[10] German Ctr Lung Res DZL, Biomed Res Endstage & Obstruct Lung Dis Hannover, Hannover, Germany
[11] Jena Univ Hosp, Inst Infect Dis & Infect Control, Jena, Germany
[12] Goethe Univ Hosp, Med Clin 1, Dept Resp Med, Frankfurt, Germany
[13] Univ Lubeck, Dept Infect Dis & Microbiol, Univ Hosp Schleswig Holstein, Campus Lubeck,Ratzeburger Allee 160, D-23538 Lubeck, Germany
关键词
CAP; Pathogens; Culture; Diagnostics; PNEUMOCOCCAL VACCINATION; HAEMOPHILUS-INFLUENZAE; IMPACT; PATHOGENS;
D O I
10.1007/s15010-021-01605-w
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
To determine the most relevant pathogens for CAP in Germany, patients with radiologically confirmed pulmonary infiltrates and at least one clinical sign of lung infection were prospectively recruited within the CAPNETZ cohort from 2004 until 2016. In 990 out of 4.672 patients (21%) receiving complete diagnostics the most prominent change of pathogens was a decrease of S. pneumoniae (58% in 2004 to 37.5% in 2016; p <= 0.001, rho = - 0.148) and an increase of H. influenzae (12.2% to 20.8%; p = 0.001, rho = 0.104).
引用
收藏
页码:533 / 537
页数:5
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