Electroactive substrates that reveal aldehyde groups for bio-immobilization

被引:51
作者
Yeo, WS
Mrksich, M
机构
[1] Univ Chicago, Dept Chem, Chicago, IL 60637 USA
[2] Univ Chicago, Inst Biophys Dynam, Chicago, IL 60637 USA
关键词
D O I
10.1002/adma.200400591
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An electroactive substrate (see Figure) that reveals aldehyde groups in response to an oxidative potential is reported. The process is based on monolayers that can be switched to initiate the selective immobilization of an amino functionalized ligand, and marks a significant advance over previous dynamic substrates that have initiated the immobilization of a ligand, since it reveals a functional group that does not require labelling of a ligand.
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页码:1352 / +
页数:6
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