Scanning Electron Microscopy of Corneal Epithelium in Soft Contact Lens Wearers

被引：18

作者：

Forte, Raimondo ^{[1
]}

Cennamo, Gilda ^{[1
]}

Del Prete, Salvatore ^{[2
]}

Cesarano, Ida ^{[1
]}

Del Prete, Antonio ^{[1
]}

机构：

[1] Univ Naples Federico II, Eye Dept, I-80131 Naples, Italy

[2] Univ Naples Federico II, I-80131 Naples, Italy

来源：

CORNEA | 2010年 / 29卷 / 07期

关键词：

scanning electron microscopy; contact lens; mucus; microvilli; HUMAN OCULAR SURFACE; MICROBIAL KERATITIS; RISK-FACTORS; MUCIN GENES; TEAR FLUID; LONG-TERM; DRY EYE; EXPRESSION; CONJUNCTIVA; SENSITIVITY;

D O I：

10.1097/ICO.0b013e3181c32f1a

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To use scanning electron microscopy (SEM) to assess differences in corneal epithelium features between soft contact lens (CL) wearers and non-CL wear control. Methods: In a cross-sectional survey, the corneal epithelium removed before photorefractive keratectomy in 10 soft CL wearers (10 eyes) and in 10 non-CL wearers (10 eyes) was evaluated with SEM. The aim of the study was to assess ultrastructural differences in corneal epithelium between the 2 groups. Results: No statistically significant difference was present between the 2 groups as concerns the number of microvilli (P = 0.19). An amount of epithelial mucus > 20% was detected in 20% of soft CL wearers and in 80% of non-CL wearers (P = 0.01). A good tolerance to CL was referred by CL wearers. Conclusion: A significant reduction of epithelial mucus at SEM evaluation was present in the CL wearers even in absence of complaints referred to CL.

引用

页码：732 / 736

页数：5

共 38 条

[21] Ocular surface epithelia express mRNA for human beta defensin-2 [J].

McNamara, NA ;

Van, R ;

Tuchin, OS ;

Fleiszig, SMJ .

EXPERIMENTAL EYE RESEARCH, 1999, 69 (05) :483-490

[22]

McNamara Nancy A, 2003, Eye Contact Lens, V29, pS10

[23] The fine structure of chromatin alterations in conjunctival epithelial cells in keratoconjunctivitis sicca [J].

Meller, D .

CORNEA, 1999, 18 (02) :225-232

[24] Clinical appearance and microscopic analysis of mucin balls associated with contact lens wear [J].

Millar, TJ ;

Papas, EB ;

Ozkan, J ;

Jalbert, I ;

Ball, M .

CORNEA, 2003, 22 (08) :740-745

[25]

MILLODOT M, 1978, ARCH OPHTHALMOL-CHIC, V96, P1225

[26] The effect of long-term, daily contact lens wear on corneal sensitivity [J].

Murphy, PJ ;

Patel, S ;

Marshall, J .

CORNEA, 2001, 20 (03) :264-269

[27]

PFISTER RR, 1973, INVEST OPHTH VISUAL, V12, P654

[28]

Pflugfelder SC, 2000, INVEST OPHTH VIS SCI, V41, P1316

[29] Ocular surface changes induced by contact lens wear [J].

Pisella, PJ ;

Malet, F ;

Lejeune, S ;

Brignole, F ;

Debbasch, C ;

Bara, J ;

Rat, P ;

Colin, J ;

Baudouin, C .

CORNEA, 2001, 20 (08) :820-825

[30] Separate oligosaccharide determinants mediate interactions of the low-molecular-weight salivary mucin with neutrophils and bacteria [J].

Prakobphol, A ;

Tangemann, K ;

Rosen, SD ;

Hoover, CI ;

Leffler, H ;

Fisher, SJ .

BIOCHEMISTRY, 1999, 38 (21) :6817-6825

← 1 2 3 4 →