The emergence of clonal chromosomal abnormalities in Philadelphia-negative cells during treatment with imatinib in patients with Philadelphia-positive chronic myeloid leukemia has been reported. We add information to this issue presenting a series of 29 patients in complete cytogenetic response after imatinib treatment, three of whom developed clonal aberrations.
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IRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Iurlo, Alessandra
Latagliata, Roberto
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Univ Roma La Sapienza, Div Hematol, Dept Cellular Biotechnol & Hematol, I-00185 Rome, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Latagliata, Roberto
Bucelli, Cristina
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Univ Milan, Maggiore Policlin Hosp Fdn, IRCCS Ca Granda, Oncohematol Div, Milan, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Bucelli, Cristina
Ferrero, Dario
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Dept Med & Expt Oncol, Chair Hematol, Turin, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Ferrero, Dario
Castagnetti, Fausto
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Univ Bologna, Sch Med, Bologna, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Castagnetti, Fausto
Breccia, Massimo
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Univ Roma La Sapienza, Dipartimento Ematol & Biotecnol, Rome, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Breccia, Massimo
Abruzzese, Elisabetta
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S Eugenio Hosp, Hematol, Rome, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Abruzzese, Elisabetta
Cattaneo, Daniele
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IRCCS Maggiore Policlin Hosp Fdn, Dept Hematol, Milan, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Cattaneo, Daniele
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Fava, Carmen
Gozzini, Antonella
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AOU Careggi, Hematol Unit, Florence, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Gozzini, Antonella
Annunziata, Mario
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Osped Cardarelli, Hematol, Naples, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Annunziata, Mario
Tiribelli, Mario
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Azienda Osped Univ Udine, Div Hematol & BMT, Dept Expt & Clin Med Sci, Udine, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Tiribelli, Mario
Pregno, Patrizia
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Az Osped Citta Salute & Sci Torino, Hematol Unit, Turin, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Pregno, Patrizia
Stagno, Fabio
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AOU Policlin, Sect Hematol, Catania, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Stagno, Fabio
Vigneri, Paolo
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Univ Catania, Sch Med, Dept Clin & Expt Med, Catania, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Vigneri, Paolo
Cavazzini, Francesco
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Univ Ferrara, Dept Haematol, I-44100 Ferrara, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Cavazzini, Francesco
Binotto, Gianni
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Univ Padua, Dept Med, Hematol & Clin Immunol Sect, Padua, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Binotto, Gianni
Mansueto, Giovanna
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CROB, Dept Oncohematol, IRCCS, Rionero In Vulture, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Mansueto, Giovanna
Russo, Sabina
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Univ Messina, Hematol Unit, Messina, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Russo, Sabina
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Falzetti, Franca
Montefusco, Enrico
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St Andrea Hosp, Hematol Unity, Rome, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Montefusco, Enrico
Gugliotta, Gabriele
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Univ Bologna, Sch Med, Seragnoli Inst Hematol, Bologna, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Gugliotta, Gabriele
Gasbarrino, Cristiana
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Univ Cattolica Giovanni Paolo II, Oncohematol Unit, Campobasso, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Gasbarrino, Cristiana
D'Addosio, Ada
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Villa San Pietro Hosp, Hematol, Rome, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
D'Addosio, Ada
Cortesi, Laura
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IRCCS, Ist Ric Farmacol, Dept Neurosci, Milan, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Cortesi, Laura
Cedrone, Michele
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San Giovanni Addolorata Hosp, UOC Hematol, Rome, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Cedrone, Michele
Rossi, Antonella Russo
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Univ Bari, Hematol, Bari, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Rossi, Antonella Russo
Avanzini, Paolo
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Santa Maria Nuova Hosp, Hematol, Reggio Emilia, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Avanzini, Paolo
Endri, Mauro
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Pordenone Hosp, Hematol Unit, Pordenone, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Endri, Mauro
Spadea, Antonio
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Ist Regina Elena, Clin Oncol, I-00161 Rome, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Spadea, Antonio
Celesti, Francesca
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Belcolle Hosp, Hematol, Viterbo, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Celesti, Francesca
Giglio, Gianfranco
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Cardarelli Hosp, Hematol, Campobasso, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Giglio, Gianfranco
Isidori, Alessandro
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AORMN Hosp, Hematol & Stem Cell Transplant Ctr, Pesaro, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Isidori, Alessandro
Crugnola, Monica
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Univ Parma, Clin & Expt Med, I-43100 Parma, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Crugnola, Monica
Calistri, Elisabetta
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Osped Ca Foncello, Hematol Unit, Treviso, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Calistri, Elisabetta
Sora, Federica
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Univ Cattolica Sacro Cuore, Rome, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Sora, Federica
Rege-Cambrin, Giovanna
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Univ Turin, San Luigi Gonzaga Univ Hosp, Div Hematol & Internal Med, Orbassano, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Rege-Cambrin, Giovanna
Sica, Simona
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Univ Cattolica Sacro Cuore, Inst Hematol, I-00168 Rome, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Sica, Simona
Luciano, Luigia
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Univ Naples Federico II, Naples, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Luciano, Luigia
Orlandi, Ester Maria
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Fdn IRCCS Policlin San Matteo, Dept Hematol Oncol, Pavia, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Orlandi, Ester Maria
Bocchia, Monica
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Univ Siena, Dept Hematol & Transplants, I-53100 Siena, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Bocchia, Monica
Tettamanti, Mauro
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IRCCS, Ist Ric Farmacol Mario Negri, Dept Neurosci, Milan, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Tettamanti, Mauro
Alimena, Giuliana
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Univ Roma La Sapienza, Dept Cellular Biotechnol & Hematol, Rome, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Alimena, Giuliana
Saglio, Giuseppe
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Univ Torino, Clin Internal Med & Hematol, Osped San Luigi, I-10043 Orbassano, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Saglio, Giuseppe
Rosti, Gianantonio
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Dept Hematol & Oncol Sci, Bologna, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Rosti, Gianantonio
Nobili, Alessandro
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IRCCS, Ist Ric Farmacol Mario Negri, Dept Neurosci, Milan, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy
Nobili, Alessandro
Mannucci, Pier Mannuccio
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Osped Maggiore Policlin, Fdn IRCCS Ca Granda, Sci Direct, Milan, ItalyIRCCS Maggiore Policlin Hosp Fdn, Div Hematol, Milan, Italy