Cancer and Pregnancy: A Comprehensive Review

被引：28

作者：

Schwab, Roxana ^{[1
]}

Anic, Katharina ^{[1
]}

Hasenburg, Annette ^{[1
]}

机构：

[1] Johannes Gutenberg Univ Mainz, Dept Obstet & Womens Hlth, Univ Med Ctr, D-55131 Mainz, Germany

来源：

CANCERS | 2021年 / 13卷 / 12期

关键词：

cancer; pregnancy; diagnostic procedures; therapeutic procedures; fetal outcome; BREAST-CANCER; GYNECOLOGIC CANCERS; FERTILITY PRESERVATION; TARGETED AGENTS; OVARIAN-TUMORS; CHEMOTHERAPY; WOMEN; MANAGEMENT; GUIDELINES; OUTCOMES;

D O I：

10.3390/cancers13123048

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Simple Summary The co-occurrence of cancer and pregnancy is fortunately a rare event. It is a challenging situation for all involved parties, as the risks and benefits of oncological treatments should be balanced for both the mother and the offspring. This work offers guidance to clinicians regarding the choice of diagnostic and therapeutic procedures, as well as regarding the management of the pregnancy. Cancer diagnosis and treatment in pregnant women is a challenging situation. A multidisciplinary network of specialists is required to guide both, the expecting mother and the unborn child through the diagnostic workup and the cytotoxic therapy, by balancing the respective risks and benefits. Tumor entity, stage, biology and gestational week at diagnosis determine the appropriate approach. As premature delivery emerged as one of the main risk factors for adverse long-term outcome of the progeny, it should be avoided, if reasonable from the oncological perspective. This article offers a comprehensive review with respect to the various aspects of cancer in pregnancy.

引用

页数：21

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