β-lactamase gene expression in a penicillin-resistant Bacillus anthracis strain

被引：73
作者：
Chen, YH
Tenover, FC
Koehler, TM
机构：
[1] Univ Texas, Hlth Sci Ctr, Sch Med, Dept Microbiol & Mol Genet, Houston, TX 77030 USA
[2] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 12期
关键词：
D O I：
10.1128/AAC.48.12.4873-4877.2004
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Expression of the bla1 and bla2 genes in an archetypal Bacillus anthracis strain is insufficient for penicillin resistance. In a penicillin-resistant clinical isolate, both genes are highly transcribed, but bla1 is the major contributor to high-level resistance to ampicillin. Differential expression of the bla genes is dependent upon strain background.
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页码：4873 / 4877
页数：5
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