Facile synthesis of thiourea derivatives in ionic liquid

被引：10
作者：
Xiao, Min Liang
Chen, Feng Huang
Chen, Zhi Juan
Ouo, Bao Shou
Lv, Xian Hai
Tang, Wen Ming [1 ]
机构：
[1] Guizhou Univ, Ctr Res & Dev Fine Chem, Guiyang 550025, Peoples R China
[2] Guiyang Environm Monitoring Ctr, Guiyang 550001, Peoples R China
[3] Anhui Univ, Sch Sci, Hefei 230036, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2007年 / 18卷 / 03期
关键词：
ionic liquid; cinnamoyl isothiocyanate; substituted aniline; cinnamoyl thiourea derivatives; synthesis;
D O I：
10.1016/j.cclet.2007.01.036
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of cinnamoyl thiourea derivatives from cinnamoyl isothiocyanate (CIT) with substituted aniline (RC6HNNH2) was investigated in the mostly used ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate, [Bmim][BF4]. Significant enhancements in reactivity, yield and reaction rate were achieved. The products could be recovered by simple filtration. [Bmim][BF4] could be recycled simply by removing water under vacuum and reused at least 9 times without significant decrease in activity. (c) 2007 Wen Ming Tang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码：258 / 260
页数：3
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