Imaging findings of leukemic involvement of the pancreaticobiliary system in adults

OBJECTIVE. Our objective was to review the imaging findings of patients with leukemic involvement of the pancreaticobiliary system in adults. CONCLUSION. Pancreatic myeloid and lymphoid leukemia show single or multiple mass lesions of homogeneous low attenuation and poor contrast enhancement on CT that is radiographically indistinguishable from that of pancreatic lymphoma. Although more cases are needed for confirmation, leukemic infiltration of the biliary tract is characterized by wall thickening of the bile duct with minimal contrast enhancement - a feature that may be helpful in differentiating it from infiltrating hilar or extrahepatic cholangiocarcinoma.