Treatment of latent tuberculosis infection in patients aged ≥35 years

被引：28

作者：

Gilroy, SA

Rogers, MAM

Blair, DC

机构：

[1] SUNY Upstate Med Univ, Dept Med, Div Infect Dis, Syracuse, NY 13210 USA

[2] SUNY Upstate Med Univ, Dept Epidemiol, Syracuse, NY 13210 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2000年 / 31卷 / 03期

关键词：

D O I：

10.1086/314037

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Treating patients aged greater than or equal to 35 years for tuberculosis infection has been controversial because of the hepatotoxic effects of isoniazid. A 2-year retrospective cohort study of outpatient medical records determined the completion rate in this age group and identified risk factors associated with isoniazid-associated hepatotoxicity. Isoniazid preventative therapy was well tolerated. However, toxicity occurred in women receiving concomitant medications and men who used alcohol.

引用

页码：826 / 829

页数：4

共 14 条

[1]

American Thoracic Society, 1967, AM REV RESPIR DIS, V96, P558

[2]

BAILEY WC, 1983, AM REV RESPIR DIS, V127, P790

[3]

BAILEY WC, 1985, CHEST, V87, P1285

[4]

BARLOW PB, 1974, AM REV RESPIR DIS, V110, P371

[5]

BLACK M, 1975, GASTROENTEROLOGY, V69, P289

[6] ISONIAZID CHEMOPROPHYLAXIS - ASSOCIATION WITH DETECTION AND INCIDENCE OF LIVER TOXICITY [J].

BYRD, RB ;

HORN, BR ;

GRIGGS, GA ;

SOLOMON, DA .

ARCHIVES OF INTERNAL MEDICINE, 1977, 137 (09) :1130-1133

[7] ISONIAZID-ASSOCIATED HEPATITIS - REPORT OF AN OUTBREAK [J].

GARIBALDI, RA ;

FEREBEE, SH ;

GREGG, MB ;

DRUSIN, RE .

AMERICAN REVIEW OF RESPIRATORY DISEASE, 1972, 106 (03) :357-+

[8] ISONIAZID PREVENTIVE THERAPY FOR TUBERCULOSIS - DECISION-ANALYSIS CONSIDERING ETHNICITY AND GENDER [J].

JORDAN, TJ ;

LEWIT, EM ;

REICHMAN, LB .

AMERICAN REVIEW OF RESPIRATORY DISEASE, 1991, 144 (06) :1357-1360

[9] ISONIAZID HEPATITIS [J].

MADDREY, WC ;

BOITNOTT, JK .

ANNALS OF INTERNAL MEDICINE, 1973, 79 (01) :1-12

[10]

*NAT CTR PREV SERV, 1994, COR CURR TUB

← 1 2 →