Hexamethylenetetraamine-bromine catalyzed rapid and efficient synthesis of bis(indolyl)methanes

被引：0

作者：

Bandgar, BP ^{[1
]}

Bettigeri, SV ^{[1
]}

Joshi, NS ^{[1
]}

机构：

[1] Swami Ramanand Teerth Marathwada Univ, Sch Chem Sci, Organ Chem Res Lab, Vishnupuri 431606, Nanded, India

来源：

MONATSHEFTE FUR CHEMIE | 2004年 / 135卷 / 10期

关键词：

aldehydes; ketones; indoles; electrophilic substitution reactions;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Highly rapid and convenient syntheses of bis(indolyl)methanes in excellent yields were carried out using the inexpensive and easily available catalyst, hexamethylenetetraamine-bromine (HMTAB). Mild reaction conditions, short reaction times, and excellent yields are important features of this method.

引用

页码：1265 / 1273

页数：9

共 21 条

[1] A convenient method of synthesis of bis-indolylmethanes:: Indium trichloride catalyzed reactions of indole with aldehydes and Schiff's bases. [J].

Babu, G ;

Sridhar, N ;

Perumal, PT .

SYNTHETIC COMMUNICATIONS, 2000, 30 (09) :1609-1614

[2] VIBRINDOLE-A, A METABOLITE OF THE MARINE BACTERIUM, VIBRIO-PARAHAEMOLYTICUS, ISOLATED FROM THE TOXIC MUCUS OF THE BOXFISH OSTRACION-CUBICUS [J].

BELL, R ;

CARMELI, S ;

SAR, N .

JOURNAL OF NATURAL PRODUCTS-LLOYDIA, 1994, 57 (11) :1587-1590

[3] FURTHER BROMINATED BIS-INDOLE AND TRIS-INDOLE ALKALOIDS FROM THE DEEP-WATER NEW-CALEDONIAN MARINE SPONGE ORINA SP [J].

BIFULCO, G ;

BRUNO, I ;

RICCIO, R ;

LAVAYRE, J ;

BOURDY, G .

JOURNAL OF NATURAL PRODUCTS-LLOYDIA, 1995, 58 (08) :1254-1260

[4] LEWIS-ACID-INDUCED ELECTROPHILIC SUBSTITUTION IN INDOLES WITH ACETONE .2. [J].

CHATTERJEE, A ;

MANNA, S ;

BANERJI, J ;

PASCARD, C ;

PRANGE, T ;

SHOOLERY, JN .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1980, (02) :553-555

[5] Lewis acid-catalyzed reactions in protic media. Lanthanide-catalyzed reactions of indoles with aldehydes or ketones [J].

Chen, DP ;

Yu, LB ;

Wang, PG .

TETRAHEDRON LETTERS, 1996, 37 (26) :4467-4470

[6] PORPHYRINOGENS AND PORPHODIMETHENES, INTERMEDIATES IN SYNTHESIS OF MESO-TETRAPHENYLPORPHINS FROM PYRROLES AND BENZALDEHYDE [J].

DOLPHIN, D .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1970, 7 (02) :275-&

[7]

Ehrlich P., 1901, MED WOCHE, P151

[8] 6-BROMOTRYPTAMINE DERIVATIVES FROM THE GULF OF CALIFORNIA TUNICATE DIDEMNUM-CANDIDUM [J].

FAHY, E ;

POTTS, BCM ;

FAULKNER, DJ ;

SMITH, K .

JOURNAL OF NATURAL PRODUCTS, 1991, 54 (02) :564-569

[9] Indolyl carboxylic acids by condensation of indoles with α-keto acids [J].

Garbe, TR ;

Kobayashi, M ;

Shimizu, N ;

Takesue, N ;

Ozawa, M ;

Yukawa, H .

JOURNAL OF NATURAL PRODUCTS, 2000, 63 (05) :596-598

[10]

KOBAYASHI S, 1995, TETRAHEDRON LETT, V36, P5773, DOI 10.1016/00404-0399(50)1096Z-

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