A Green, Inexpensive and Efficient Organocatalyzed Procedure for Aqueous Aldol Condensations

被引：12

作者：

Abaee, M. Saeed ^{[1
]}

Mojtahedi, Mohammad M. ^{[1
]}

Forghani, Soudabeh ^{[1
]}

Ghandchi, Nafiseh M. ^{[2
]}

Forouzani, Mehdi ^{[3
]}

Sharifi, Roholah ^{[1
]}

Chaharnazm, Behnam ^{[3
]}

机构：

[1] Chem & Chem Engn Res Ctr Iran, Fac Organ Chem & Nat Prod, Tehran 1496813151, Iran

[2] Islamic Azad Univ, Dept Chem, Tehran Cent Branch, Tehran 1467686831, Iran

[3] Payam Noor Univ, Dept Chem, Sari Ctr, Sari 4818858565, Iran

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2009年 / 20卷 / 10期

关键词：

aldol condensation; aqueous conditions; organocatalyst; bisarylmethylidenes; chalcones; SUPERPARAMAGNETIC IRON-OXIDE; SOLVENT-FREE SYNTHESIS; ORGANIC-REACTIONS; FACILE SYNTHESIS; ONE-POT; CATALYST; ALDEHYDES; EPOXIDES; MEDIA; WATER;

D O I：

10.1590/S0103-50532009001000018

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile and general procedure is presented for diethylamine-catalyzed double crossed aldol condensation of cyclic ketones with various aromatic aldehydes under aqueous conditions. Excellent yields of 3,5-bisarylmethylidenes of homocyclic and heterocyclic ketones are achieved in a one-pot procedure. Furthermore, the methodology is efficiently applied to the synthesis of chalcones from their corresponding methyl ketones. In the majority of the cases studied, products precipitate from the reaction mixtures and the medium is recycled in subsequent several reactions without significant loss of activity.

引用

页码：1895 / S21

页数：27

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