Hypoproteinemia predicts disease severity and mortality in COVID-19: a call for action

被引：26
|
作者：
Ali, Amira Mohammed [1 ,2 ]
Kunugi, Hiroshi [1 ,3 ]
机构：
[1] Natl Ctr Neurol & Psychiat, Natl Inst Neurosci, Dept Mental Disorder Res, Tokyo, Japan
[2] Alexandria Univ, Fac Nursing, Dept Psychiat Nursing & Mental Hlth, Alexandria, Egypt
[3] Teikyo Univ, Dept Psychiat, Sch Med, Tokyo, Japan
来源：
DIAGNOSTIC PATHOLOGY | 2021年 / 16卷 / 01期
关键词：
Hypoproteinemia; *albumin*; Blood urea nitrogen; Disease severity; Mortality; Coronavirus disease 2019; COVID-19; Multiple organ failure; Intensive care unit; Malnutrition;
D O I：
10.1186/s13000-021-01092-5
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Proteins represent the major building blocks of body tissues, and they regulate signaling involved in most cellular activities. Coronavirus disease 2019 (COVID-19) infection has been associated with high fatality, especially among older adults. The main cause of death is pulmonary tissue damage and multiple organ failure. The disease is associated with a hypercatabolic state that entails excessive protein loss. This review commentary sheds the light on hypoproteinemia in symptomatic/hospitalized COVID-19 with a special emphasis on its pathophysiology, screening, as well as its contribution to disease severity and adverse effects.
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页数：3
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