Hypoproteinemia predicts disease severity and mortality in COVID-19: a call for action

被引：27

作者：

Ali, Amira Mohammed ^{[1
,2
]}

Kunugi, Hiroshi ^{[1
,3
]}

机构：

[1] Natl Ctr Neurol & Psychiat, Natl Inst Neurosci, Dept Mental Disorder Res, Tokyo, Japan

[2] Alexandria Univ, Fac Nursing, Dept Psychiat Nursing & Mental Hlth, Alexandria, Egypt

[3] Teikyo Univ, Dept Psychiat, Sch Med, Tokyo, Japan

来源：

DIAGNOSTIC PATHOLOGY | 2021年 / 16卷 / 01期

关键词：

Hypoproteinemia; *albumin*; Blood urea nitrogen; Disease severity; Mortality; Coronavirus disease 2019; COVID-19; Multiple organ failure; Intensive care unit; Malnutrition;

D O I：

10.1186/s13000-021-01092-5

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Proteins represent the major building blocks of body tissues, and they regulate signaling involved in most cellular activities. Coronavirus disease 2019 (COVID-19) infection has been associated with high fatality, especially among older adults. The main cause of death is pulmonary tissue damage and multiple organ failure. The disease is associated with a hypercatabolic state that entails excessive protein loss. This review commentary sheds the light on hypoproteinemia in symptomatic/hospitalized COVID-19 with a special emphasis on its pathophysiology, screening, as well as its contribution to disease severity and adverse effects.

引用

页数：3

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