Controllable Photodynamic Therapy Implemented by Regulating Singlet Oxygen Efficiency

被引:151
作者
Wu, Wenting [1 ,2 ]
Shao, Xiaodong [1 ]
Zhao, Jianzhang [2 ]
Wu, Mingbo [1 ]
机构
[1] China Univ Petr, State Key Lab Heavy Oil Proc, Qingdao 266580, Peoples R China
[2] Dalian Univ Technol, Sch Chem Engn, State Key Lab Fine Chem, Dalian 116024, Peoples R China
基金
中国博士后科学基金;
关键词
cancer; photodynamic therapy; photosensitization; singlet oxygen; INTRAMOLECULAR CHARGE-TRANSFER; RESONANCE ENERGY-TRANSFER; RATIOMETRIC FLUORESCENT-PROBE; PHOTOINDUCED ELECTRON-TRANSFER; FIBROBLAST ACTIVATION PROTEIN; TRIPLET EXCITED-STATES; MOLECULAR LOGIC; HIGHLY EFFICIENT; GRAPHENE OXIDE; CANCER-CELLS;
D O I
10.1002/advs.201700113
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
With singlet oxygen (O-1(2)) as the active agent, photodynamic therapy (PDT) is a promising technique for the treatment of various tumors and cancers. But it is hampered by the poor selectivity of most traditional photosensitizers (PS). In this review, we present a summary of controllable PDT implemented by regulating singlet oxygen efficiency. Herein, various controllable PDT strategies based on different initiating conditions (such as pH, light, H2O2 and so on) have been summarized and introduced. More importantly, the action mechanisms of controllable PDT strategies, such as photoinduced electron transfer (PET), fluorescence resonance energy transfer (FRET), intramolecular charge transfer (ICT) and some physical/chemical means (e.g. captivity and release), are described as a key point in the article. This review provide a general overview of designing novel PS or strategies for effective and controllable PDT.
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页数:21
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共 179 条
[1]   Self-Assembled Peptide- and Protein-Based Nanomaterials for Antitumor Photodynamic and Photothermal Therapy [J].
Abbas, Manzar ;
Zou, Qianli ;
Li, Shukun ;
Yan, Xuehai .
ADVANCED MATERIALS, 2017, 29 (12)
[2]   Tuning Photosensitized Singlet Oxygen Generation Efficiency of Novel Aza-BODIPY Dyes [J].
Adarsh, Nagappanpillai ;
Avirah, Rekha R. ;
Ramaiah, Danaboyina .
ORGANIC LETTERS, 2010, 12 (24) :5720-5723
[3]   Photodynamic Therapy of Cancer: An Update [J].
Agostinis, Patrizia ;
Berg, Kristian ;
Cengel, Keith A. ;
Foster, Thomas H. ;
Girotti, Albert W. ;
Gollnick, Sandra O. ;
Hahn, Stephen M. ;
Hamblin, Michael R. ;
Juzeniene, Asta ;
Kessel, David ;
Korbelik, Mladen ;
Moan, Johan ;
Mroz, Pawel ;
Nowis, Dominika ;
Piette, Jacques ;
Wilson, Brian C. ;
Golab, Jakub .
CA-A CANCER JOURNAL FOR CLINICIANS, 2011, 61 (04) :250-281
[4]   Tyrosine conjugated zinc(II) phthalocyanine for photodynamic therapy: Synthesis and photophysicochemical properties [J].
Aliosman, Meliha ;
Goksel, Meltem ;
Mantareva, Vanya ;
Stoineva, Ivanka ;
Durmus, Mahmut .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2017, 334 :101-106
[5]   Reversible binding of oxygen to aromatic compounds [J].
Aubry, JM ;
Pierlot, C ;
Rigaudy, J ;
Schmidt, R .
ACCOUNTS OF CHEMICAL RESEARCH, 2003, 36 (09) :668-675
[6]   Singlet Oxygen Generation by Novel NIR BODIPY Dyes [J].
Awuah, Samuel G. ;
Polreis, Jason ;
Biradar, Vidya ;
You, Youngjae .
ORGANIC LETTERS, 2011, 13 (15) :3884-3887
[7]   Fluorescence resonance energy transfer between bovine serum albumin and fluoresceinamine [J].
Bai, Zhijun ;
Liu, Yushuang ;
Zhang, Ping ;
Guo, Jun ;
Ma, Yuxing ;
Yun, Xiaoling ;
Zhao, Xinmin ;
Zhong, Ruibo ;
Zhang, Feng .
LUMINESCENCE, 2016, 31 (03) :688-693
[8]   Photodynamic therapy via FRET following bioorthogonal click reaction in cancer cells [J].
Bio, Moses ;
Rajaputra, Pallavi ;
You, Youngjae .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (01) :145-148
[9]   Ruthenium porphyrin-induced photodamage in bladder cancer cells [J].
Bogoeva, Vanya ;
Siksjo, Monica ;
Saeterbo, Kristin G. ;
Melo, Thor Bernt ;
Bjorkoy, Astrid ;
Lindgren, Mikael ;
Gederaas, Odrun A. .
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2016, 14 :9-17
[10]   Surface-Induced Selection During In Situ Photoswitching at the Solid/Liquid Interface [J].
Bonacchi, Sara ;
El Garah, Mohamed ;
Ciesielski, Artur ;
Herder, Martin ;
Conti, Simone ;
Cecchini, Marco ;
Hecht, Stefan ;
Samori, Paolo .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (16) :4865-4869