Assessing risk and managing Mycobacterium tuberculosis infection and disease in patients due to start anti-TNFα treatment

被引:4
作者
Ormerod, LP [1 ]
机构
[1] Blackburn Royal Infirm, Chest Clin, Blackburn BB2 3LR, Lancs, England
[2] Univ Cent Lancashire, Lancashire Postgrad Sch Med & Hlth, Preston PR1 2HE, Lancs, England
关键词
tuberculosis; latent infection; anti-TNF-alpha treatment;
D O I
10.1016/j.cyto.2004.07.013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This short paper describes the, rationale being applied in the United Kingdom to the problem of treating latent TB infection in persons requiring anti-TNF-alpha treatment. This will largely have to be done by an individual risk/benefit analysis based on the risks of developing disease from national epidemiology compared with the risks of significant hepatotoxicity from treatment of latent infection. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:179 / 181
页数:3
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