Neoderodanes from Teucrium orientale

被引:16
作者
Bruno, M
Rosselli, S
Maggio, A
Piozzi, F
Scaglioni, L
Arnold, NA
Simmonds, MSJ [1 ]
机构
[1] Royal Bot Gardens, Jodrell Lab, Richmond TW9 3AB, Surrey, England
[2] Univ Palermo, Dipartimento Chim Organ E Paterno, I-90128 Palermo, Italy
[3] Univ Milan, Dipartimento Sci Mol Agroaliment, I-20133 Milan, Italy
[4] Univ St Esprit, Fac Agron, Beirut, Lebanon
关键词
lamiaceae; Teucrium orientale; structure elucidation; neo-clerodane diterpenoid; antifeedant activity;
D O I
10.1248/cpb.52.1497
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new neoclerodane diterpenoids, 6-deacetyl-teucrolivin A (5) and 8beta-hydroxy-teucrolivin B (6), were isolated from the aerial parts of Teucrium orientale, along with four already known neoclerodane diterpenoids, teucrolivin A (1), teucrolivin B (2), teucrolivin C (3) and teucrolivin H (4), previously isolated from Teucrium oliverianum. Their structures were elucidated on the basis of spectroscopic evidence and chemical transformations. Compounds 1-3 were assayed for antifeedant activity against Spodoptera littoralis, S. frugiperda and Heliocoverpa armigera. Teucrolivin A was the most potent of the three compounds tested.
引用
收藏
页码:1497 / 1500
页数:4
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