Neoderodanes from Teucrium orientale

被引:16
作者
Bruno, M
Rosselli, S
Maggio, A
Piozzi, F
Scaglioni, L
Arnold, NA
Simmonds, MSJ [1 ]
机构
[1] Royal Bot Gardens, Jodrell Lab, Richmond TW9 3AB, Surrey, England
[2] Univ Palermo, Dipartimento Chim Organ E Paterno, I-90128 Palermo, Italy
[3] Univ Milan, Dipartimento Sci Mol Agroaliment, I-20133 Milan, Italy
[4] Univ St Esprit, Fac Agron, Beirut, Lebanon
关键词
lamiaceae; Teucrium orientale; structure elucidation; neo-clerodane diterpenoid; antifeedant activity;
D O I
10.1248/cpb.52.1497
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new neoclerodane diterpenoids, 6-deacetyl-teucrolivin A (5) and 8beta-hydroxy-teucrolivin B (6), were isolated from the aerial parts of Teucrium orientale, along with four already known neoclerodane diterpenoids, teucrolivin A (1), teucrolivin B (2), teucrolivin C (3) and teucrolivin H (4), previously isolated from Teucrium oliverianum. Their structures were elucidated on the basis of spectroscopic evidence and chemical transformations. Compounds 1-3 were assayed for antifeedant activity against Spodoptera littoralis, S. frugiperda and Heliocoverpa armigera. Teucrolivin A was the most potent of the three compounds tested.
引用
收藏
页码:1497 / 1500
页数:4
相关论文
共 29 条
[11]   Screening of some Greek aromatic plants for antioxidant activity [J].
Couladis, M ;
Tzakou, O ;
Verykokidou, E ;
Harvala, C .
PHYTOTHERAPY RESEARCH, 2003, 17 (02) :194-195
[12]   TEUCROLIVINS-D-F, NEOCLERODANE DERIVATIVES FROM TEUCRIUM-OLIVERIANUM [J].
DELATORRE, MC ;
BRUNO, M ;
PIOZZI, F ;
SAVONA, G ;
RODRIGUEZ, B ;
OMAR, AA .
PHYTOCHEMISTRY, 1991, 30 (05) :1603-1606
[13]   2 NEOCLERODANE DITERPENOIDS CONTAINING AN UNUSUAL 2,6-DIOXABICYCLO[2.2.1]HEPTANE STRUCTURAL MOIETY [J].
DELATORRE, MC ;
BRUNO, M ;
PIOZZI, F ;
SAVONA, G ;
OMAR, AA ;
PERALES, A ;
RODRIGUEZ, B .
TETRAHEDRON, 1991, 47 (20-21) :3463-3470
[14]  
Fernandez P. B., 1997, J ETHNOPHARMACOL, V55, P93
[15]   Effects of Teucrium divaricatum Heldr. ssp divaricatum decoction on experimental ulcer in rats [J].
Galati, EM ;
Mondello, MR ;
D'Aquino, A ;
Miceli, N ;
Sanogo, R ;
Tzakou, O ;
Monforte, MT .
JOURNAL OF ETHNOPHARMACOLOGY, 2000, 72 (1-2) :337-342
[16]   Insect antifeedant activity of clerodane diterpenes and related model compounds [J].
Gebbinck, EAK ;
Jansen, BJM ;
de Groot, A .
PHYTOCHEMISTRY, 2002, 61 (07) :737-770
[17]   HYPOGLYCEMIC EFFECTS OF TEUCRIUM-POLIUM [J].
GHARAIBEH, MN ;
ELAYAN, HH ;
SALHAB, AS .
JOURNAL OF ETHNOPHARMACOLOGY, 1988, 24 (01) :93-99
[18]  
GREUTER W, 1986, MED CHECKLIST, V3, P366
[19]  
NAGAO Y, 1982, CHEM PHARM BULL, V30, P727
[20]   Further furoclerodanes from Teucrium genus [J].
Piozzi, F ;
Bruno, M ;
Rosselli, S .
HETEROCYCLES, 1998, 48 (10) :2185-2203