Effects of haw pectic oligosaccharide on lipid metabolism and oxidative stress in experimental hyperlipidemia mice induced by high-fat diet

被引：95
|
作者：
Li, Tuoping [1 ]
Li, Suhong [2 ]
Du, Lijuan [1 ]
Wang, Na [3 ]
Guo, Mei [3 ]
Zhang, Junwei [1 ]
Yan, Fenwen [1 ]
Zhang, Huili [1 ]
机构：
[1] Liaoning Univ, Dept Food Sci, Shenyang 110036, Peoples R China
[2] Shenyang Normal Univ, Dept Food Sci, Shenyang 110034, Peoples R China
[3] Tianjin Agr Univ, Dept Food Sci, Tianjin 300384, Peoples R China
来源：
FOOD CHEMISTRY | 2010年 / 121卷 / 04期
关键词：
Haw; Pectic oligosaccharide; Hyperlipidemia; Antioxidant; Total cholesterol; Triglyceride;
D O I：
10.1016/j.foodchem.2010.01.039
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The anti-hyperlipidemic and antioxidant effects of haw pectic oligosaccharide (HPOS) were investigated using a model of hyperlipidemia induced by a high-fat diet in mice. HPOS significantly lowered the serum levels of total cholesterol (p < 0.01) and triglycerides (p < 0.05) and inhibited the accumulation of body fat in this model. It significantly enhanced the activity of superoxide dismutase to suppress oxidative reactions (p < 0.01) and inhibited the synthesis and accumulation of malondialdehyde in serum (p < 0.05). Thus, HPOS could be valuable in the development of nutritional and drug therapies to combat cardiovascular diseases. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1010 / 1013
页数：4
相关论文
共 50 条
  • [21] Noni (Morinda citrifoliaL.) wine prevents the oxidative stress and obesity in mice induced by high-fat diet
    Zhang, Kai
    Meng, Jun
    Li, Xiaojuan
    Tang, Xue
    Ma, Shuhua
    Lv, Yipin
    Yang, Shaojun
    JOURNAL OF FOOD BIOCHEMISTRY, 2020, 44 (11)
  • [22] ASTAXANTHIN PREVENTS HEPATOSTEATOSIS AND HYPERLIPIDEMIA BUT NOT OBESITY IN HIGH-FAT DIET FED MICE
    Nguyen-Le, Duy
    Ngo-My, Tien
    Vo-Minh, Tuan
    Nguyen, Cao-Tri
    Tran, Thuoc Linh
    Tran-Van, Hieu
    JOURNAL OF MICROBIOLOGY BIOTECHNOLOGY AND FOOD SCIENCES, 2023, 12 (05):
  • [23] Beneficial effects of natural Jeju groundwaters on lipid metabolism in high-fat diet-induced hyperlipidemic rats
    Wang, Yan-chao
    Lu, Jin-miao
    Jin, Hui-zi
    Ma, Ai-niu
    Zhang, Jin-yang
    Gong, Nian
    Xiao, Qi
    Zhu, Bin
    Lv, Ying-fang
    Yu, Na
    Zhang, Wei-dong
    Wang, Yong-xiang
    NUTRITION RESEARCH AND PRACTICE, 2014, 8 (02) : 165 - 171
  • [24] Hawthorn pectin mitigates high-fat diet induced hyperlipidemia in mice through promoting Dubosiella newyorkensis
    Zhao, Qianyun
    Liu, Yubin
    Li, Mingxing
    Zhao, Long
    Wang, Tiangang
    Xiao, Yaqin
    Wei, Shulin
    Wu, Ke
    Yang, Jiayue
    Wang, Yaqiu
    Zhao, Yueshui
    Du, Fukuan
    Chen, Yu
    Deng, Shuai
    Shen, Jing
    Xiao, Zhangang
    Li, Zhi
    Wang, Shengpeng
    Wu, Xu
    CARBOHYDRATE POLYMERS, 2025, 359
  • [25] Slowly Digestible Carbohydrate Diet Ameliorates Hyperglycemia and Hyperlipidemia in High-Fat Diet/Streptozocin-Induced Diabetic Mice
    Chen, Yu-Zhong
    Gu, Jia
    Chuang, Wei-Ting
    Du, Ya-Fang
    Zhang, Lin
    Lu, Meng-Lan
    Xu, Jia-Ying
    Li, Hao-Qiu
    Liu, Yan
    Feng, Hao-Tian
    Li, Yun-Hong
    Qin, Li-Qiang
    FRONTIERS IN NUTRITION, 2022, 9
  • [26] Beneficial effect of seaweed on high-fat diet-induced oxidative stress and insulin resistance in rats
    Tao Tong
    Du-Ok Ko
    Bo-Sup Kim
    Kyung-Sik Ham
    Seong-Gook Kang
    Food Science and Biotechnology, 2015, 24 : 2185 - 2191
  • [27] Beneficial effect of seaweed on high-fat diet-induced oxidative stress and insulin resistance in rats
    Tong, Tao
    Ko, Du-Ok
    Kim, Bo-Sup
    Ham, Kyung-Sik
    Kang, Seong-Gook
    FOOD SCIENCE AND BIOTECHNOLOGY, 2015, 24 (06) : 2185 - 2191
  • [28] Resveratrol ameliorates oxidative stress, inflammatory response and lipid metabolism in common carp (Cyprinus carpio) fed with high-fat diet
    Wu, Di
    Li, Jinnan
    Fan, Ze
    Wang, Liansheng
    Zheng, Xianhu
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [29] Antioxidative Potential and Ameliorative Effects of Rice Bran Fermented with Lactobacillus against High-Fat Diet-Induced Oxidative Stress in Mice
    Yin, Tingting
    Chen, Yidan
    Li, Wenzhao
    Tang, Tingting
    Li, Tong
    Xie, Binbin
    Xiao, Dong
    He, Hailun
    ANTIOXIDANTS, 2024, 13 (06)
  • [30] Modulation of fat metabolism and gut microbiota by resveratrol on high-fat diet-induced obese mice
    Campbell, C. Linda
    Yu, Renqiang
    Li, Fengzhi
    Zhou, Qin
    Chen, Daozhen
    Qi, Ce
    Yin, Yongxiang
    Sun, Jin
    DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2019, 12 : 97 - 107
12345