Kinetics and mechanism of the cleavage of N-phthaloylglycine in buffers of some primary amines

被引：0

作者：

Khan, MN ^{[1
]}

Ismail, NH

机构：

[1] Univ Malaya, Fac Sci, Dept Chem, Kuala Lumpur 50603, Malaysia

[2] Univ Teknol Mara, Fac Sci Appl, Dept Chem, Shah Alam 40450, Malaysia

来源：

JOURNAL OF CHEMICAL RESEARCH-S | 2002年 / 12期

关键词：

N-phthaloylglycine; 2-methoxyethylamine; 2-hydroxyethylamine; tris-(hydroxymethyl)aminomethane; hydrazine; aminolysis; general base catalysis;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Kinetic studies on the nucleophilic cleavage of N-phthaloylglycine (NPG) in buffers of 2-methoxyethylamine, and 2-hydroxyethylamine reveal the relationship: k(n)(app) = A(1) [Am](inverted perpendicular)/(1 + A(2) [Am](inverted perpendicular)) where A(1) and A(2) are constants (kinetic parameters) and k(n)(app) and [Am](inverted perpendicular) represent apparent nucleophilic second-order rate constant and total amine buffer concentration, respectively.

引用

页码：593 / 595

页数：3

共 16 条

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