Copper-Mediated Oxidative Trifluoromethylthiolation of Potassium Aryltrifluoroborates with Elemental Sulfur and Ruppert-Prakash Reagent

被引：7
作者：
Dubbaka, Srinivas Reddy [1 ,2 ]
Atthunuri, Azmi Reddy [1 ]
Prakash, Koraboina Chandra [1 ]
Rangabashyam, Prabhu [1 ]
Gadde, Satyanarayana [1 ]
Kothandaraman, Rajesh [1 ]
机构：
[1] Albany Mol Res Singapore Res Ctr Pte Ltd, Dept Med Chem, 61 Sci Pk Rd,05-01 Galen,Sci Pk 2, Singapore 117525, Singapore
[2] Nanyang Technol Univ, Sch Chem & Biomed Engn, 62 Nanyang Dr, Singapore 637459, Singapore
来源：
SYNTHESIS-STUTTGART | 2016年 / 48卷 / 08期
关键词：
aryl trifluoromethyl thioethers; trifluoromethylthiolation; potassium aryltrifluoroborates; copper; Ruppert-Prakash reagent; elemental sulfur; ARYL BORONIC ACIDS; HYPERVALENT IODINE REAGENT; ALPHA-FLUORINATED ETHERS; C-H ACTIVATION; MEDICINAL CHEMISTRY; CATALYZED SYNTHESIS; NUCLEOPHILIC PERFLUOROALKYLATION; SUBSTITUENT CONSTANTS; CONVENIENT SYNTHESIS; LANGLOIS REAGENT;
D O I：
10.1055/s-0035-1561565
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile procedure for the copper-mediated oxidative trifluoromethylthiolation of potassium aryl-and heteroaryltrifluoroborates with Ruppert-Prakash reagent and elemental sulfur is presented. Aryl trifluoromethyl thioethers can be prepared in good to moderate yield under mild reaction conditions.
引用
收藏
页码：1246 / 1252
页数：7
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