Hydrodynamic focusing on a silicon chip: Mixing nanoliters in microseconds

被引：718

作者：

Knight, JB ^{[1
]}

Vishwanath, A ^{[1
]}

Brody, JP ^{[1
]}

Austin, RH ^{[1
]}

机构：

[1] Princeton Univ, Dept Phys, Princeton, NJ 08544 USA

来源：

PHYSICAL REVIEW LETTERS | 1998年 / 80卷 / 17期

关键词：

D O I：

10.1103/PhysRevLett.80.3863

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We describe the formation and control of nanoscale, submerged fluid jets. The focusing process necessary to achieve these small length scales is characterized experimentally and theoretically. Fast mixing is one important application of nanoscale fluid control: We demonstrate this with a continuous-flow mixer capable of mix times of less than 10 mu s and sample consumption rates of nanoliters per second. This new technique facilitates the study of fast reaction kinetics on time scales unattainable with conventional mixing technology.

引用

页码：3863 / 3866

页数：4

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