A monoclonal antibody to high molecular weight kininogen reduces inflammation in the HLA-B27 transgenic rat model of inflammatory bowel disease and arthritis.

被引：0
|
作者：
Pixley, RA
Sainz, IM
Keith, JC
Isordia-Salas, I
Leatherby, Y
Albert, LM
Colman, RW
机构：
[1] Temple Univ, Sch Med, Sol Sherry Thrombosis Res Ctr, Philadelphia, PA 19122 USA
[2] Wyeth Ayerst Res, Cardiovasc & Metab Dis Res, Cambridge, MA USA
来源：
BLOOD | 2004年 / 104卷 / 11期
关键词：
D O I：
10.1182/blood.V104.11.3437.3437
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
3437
引用
收藏
页码：937A / 937A
页数：1
相关论文
共 34 条
  • [1] A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat
    Keith, JC
    Sainz, IM
    Salas, II
    Pixley, RA
    Leathurby, Y
    Albert, LM
    Colman, RW
    ARTHRITIS RESEARCH & THERAPY, 2005, 7 (04) : R769 - R776
  • [2] A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat
    James C Keith
    Irma M Sainz
    Irma Isordia-Salas
    Robin A Pixley
    Yelena Leathurby
    Leo M Albert
    Robert W Colman
    Arthritis Research & Therapy, 7
  • [3] Beneficial effects of estrogen treatment in the HLA-B27 transgenic rat model of inflammatory bowel disease
    Harnish, DC
    Albert, LM
    Leathurby, Y
    Eckert, AM
    Ciarletta, A
    Kasaian, M
    Keith, JC
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2004, 286 (01): : G118 - G125
  • [4] Molecular mechanism of interleukin-11 in the HLA-B27 rat model of inflammatory bowel disease.
    Peterson, RL
    Wang, L
    Albert, LM
    Keith, JC
    Dorner, AJ
    GASTROENTEROLOGY, 1998, 114 (04) : A1060 - A1060
  • [5] A monoclonal antibody to domain 5 of high molecular weight kininogen (HK) is therapeutic in a rodent model of rheumatoid arthritis.
    Espinola, R
    Uknis, A
    Sainz, I
    Isordia-Salas, I
    Agelan, A
    DeLa Cadena, R
    Pixley, R
    Colman, RW
    BLOOD, 2003, 102 (11) : 39B - 39B
  • [6] Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease
    Onderdonk, AB
    Richardson, JA
    Hammer, RE
    Taurog, JD
    INFECTION AND IMMUNITY, 1998, 66 (12) : 6022 - 6023
  • [7] Molecular effects of recombinant human interleukin-11 in the HLA-B27 rat model of inflammatory bowel disease
    Peterson, RL
    Wang, LL
    Albert, L
    Keith, JC
    Dorner, AJ
    LABORATORY INVESTIGATION, 1998, 78 (12) : 1503 - 1512
  • [8] TNFα blockade prevents the development of inflammatory bowel disease in HLA-B27 transgenic rats
    Milia, Anna Franca
    Manetti, Mirko
    Generini, Sergio
    Polidori, Lucia
    Benelli, Gemma
    Cinelli, Marina
    Messerini, Luca
    Ibba-Manneschi, Lidia
    Matucci-Cerinic, Marco
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2009, 13 (01) : 164 - 176
  • [9] HISTOPATHOLOGIC FINDINGS IN INFLAMMATORY BOWEL-DISEASE IN HLA-B27 POSITIVE (REACTIVE) ARTHRITIS
    CUVELIER, C
    DEVOS, M
    MIELANTS, H
    ROELS, H
    VEYS, E
    JOURNAL OF PATHOLOGY, 1984, 143 (01): : A3 - A3
  • [10] Pharmacogenomic analysis of rhIL-11 treatment in the HLA-B27 rat model of inflammatory bowel disease
    Peterson R.L.
    Wang L.
    Albert L.
    Marchese E.
    Erickson J.
    Wong A.
    Mounts W.M.
    Hayes L.
    Bouchard P.
    Keith J.
    Dorner A.J.
    The Pharmacogenomics Journal, 2002, 2 (6) : 383 - 399
1234