A radical approach for the construction of the tricyclic core of stemoamide

被引：26
作者：
Bogliotti, N [1 ]
Dalko, PI [1 ]
Cossy, J [1 ]
机构：
[1] ESPCI, CNRS, Lab Chim Organ Assoc, F-75231 Paris 05, France
来源：
SYNLETT | 2005年 / 02期
关键词：
radical cyclization; metathesis; stereoselective synthesis;
D O I：
10.1055/s-2004-837197
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A rapid synthesis of (+/-)-9,10-bis-epi-stemoamide is presented. Three of the four contiguous stereocenters of this compound were set in a diastereoselective radical 7-exo-trig cyclization, which also allowed the construction of the tricyclic core of the molecule.
引用
收藏
页码：349 / 351
页数：3
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