Serologic Response to Hepatitis B Vaccination in HIV-Infected Patients with Isolated Positivity for Antibodies to Hepatitis B Core Antigen

被引:25
作者
Chakvetadze, Catherine [1 ]
Bani-Sadr, Firouze [1 ]
Le Pendeven, Catherine [2 ]
Lescure, Francois-Xavier [1 ]
Fontaine, Camille [1 ]
Galperine, Tatiana [1 ]
Slama, Laurence [1 ]
Bonnard, Philippe [1 ]
Mariot, Philippe [1 ]
Soussan, Patrick [2 ]
Pialoux, Gilles [1 ]
机构
[1] Hop Tenon, Serv Malad Infect & Trop, F-75970 Paris 20, France
[2] Hop Tenon, Virol Lab, F-75970 Paris 20, France
关键词
A VACCINE; VIRUS; ADULTS; HBS; INJECTIONS; EFFICACY; NUMBER;
D O I
10.1086/651422
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We assessed the safety and immunogenicity of hepatitis B vaccination among 40 human immunodeficiency virus-infected patients with isolated positivity for antibodies to hepatitis B core antigen. No baseline factors were found to be predictive of an anamnestic response, which occurred in 32.5% of the patients. The overall response rate among patients without an anamnestic response was 74.0% after 3-6 vaccine doses.
引用
收藏
页码:1184 / 1186
页数:3
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