Obstructive Sleep Apnea Is Related to Increased Arterial Stiffness in Ultrasound Speckle-Tracking Analysis

被引：7
作者：
Tuleta, I. [1 ]
Skowasch, D. [1 ]
Krycki, J. [1 ]
Pizarro, C. [1 ]
Hammerstingl, C. [1 ]
Weber, M. [1 ]
Schahab, N. [1 ]
Nickenig, G. [1 ]
Schaefer, C. [1 ]
Pingel, S. [1 ]
机构：
[1] Univ Bonn, Dept Internal Med Cardiol Pulmonol & Angiol 2, 25 Sigmund Freud St, D-53105 Bonn, Germany
来源：
RESPIRATORY MEDICINE AND SCIENCE | 2016年 / 910卷
关键词：
Functional vessel damage; Intermittent nocturnal hypoxia; Vascular incompliance; Vessel wall deformation; Vessel wall motion; COMMON CAROTID-ARTERY; MECHANICAL-PROPERTIES; CIRCUMFERENTIAL STRAIN; RISK-FACTOR; ATHEROSCLEROSIS; DISEASE;
D O I：
10.1007/5584_2016_215
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Obstructive sleep apnea (OSA) is an independent risk factor for atherosclerosis. The aim of our study was to determine arterial stiffness in OSA patients by means of the ultrasound speckle-tracking-based method. Twenty six OSA patients and 17 control subjects were enrolled in the study. The speckle-tracking-based analysis of carotid artery included circumferential strains, circumferential strain rates, radial displacement, and radial strain rates. We found that the global average circumferential strains, circumferential strain rates, and radial displacement were significantly lower in OSA patients compared to controls (2.19 +/- 0.30 % vs. 4.17 +/- 0.33 %, 0.22 +/- 0.03 l/s vs. 0.31 +/- 0.02 l/s, 0.10 +/- 0.01 mm vs. 0.16 +/- 0.02 mm, respectively, p < 0.05 for all). There were no significant differences in radial strain rates between the groups (0.32 +/- 0.04 % vs. 0.33 +/- 0.01 %). We conclude that OSA is associated with an increased arterial stiffness.
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收藏
页码：9 / 14
页数：6
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