Voltammetric and amperometric determination of uric acid at a carbon-ceramic electrode modified with multi walled carbon nanotubes

被引：19

作者：

Habibi, Biuck ^{[1
]}

Pezhhan, Hamzhe ^{[1
]}

Pournaghi-Azar, Mohammad Hossien ^{[2
]}

机构：

[1] Azarbaijan Univ Tarbiat Moallem, Dept Chem, Electroanalyt Chem Lab, Tabriz 53714161, Iran

[2] Univ Tabriz, Fac Chem, Electroanalyt Chem Lab, Tabriz 5166616471, Iran

来源：

MICROCHIMICA ACTA | 2010年 / 169卷 / 3-4期

关键词：

Multi walled carbon nanotube; Carbon-ceramic electrode; Electrocatalysis; Uric acid; ASSEMBLED GOLD ELECTRODE; NANOPARTICLES MODIFIED ELECTRODE; ASCORBIC-ACID; ELECTROCHEMICAL-BEHAVIOR; ELECTROCATALYTIC OXIDATION; DOPAMINE; PASTE; EPINEPHRINE; BIOSENSORS; PLATFORMS;

D O I：

10.1007/s00604-010-0338-9

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The voltammetric behavior of uric acid (UA) was studied at a carbon-ceramic electrode modified with multi walled carbon nanotubes; which was developed via a simple procedure. UA can be effectively oxidized at the surface of the electrode and produced an anodic peak at about 0.29 V in pH 6.8 phosphate buffer solutions. The experimental parameters such as pH, accumulation time, and amount of multi walled carbon nanotubes were optimized for determination of UA. Under the optimum conditions, the anodic peak current in differential pulse voltammetry is linear to the UA concentration over the range from 2.5x10-7M to 1.0x10-4 M with a correlation coefficient of 0.998. The electrode exhibited good stability and could be easily regenerated. The relative standard deviation of the peak current obtained for a 5.0 x 10(-5) M UA solution was 1.0%. The influence of dopamine and ascorbic acid on the anodic peak current of UA was examined. This method was successfully applied for the determination of uric acid in human urine sample, and the recovery was 99.9%.

引用

页码：313 / 320

页数：8

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