EFFECT OF SOYBEAN DIET ON SERUM LIPIDS AN LIPOPROTEINS OF POSTMENOPAUSAL WOMEN

被引：0
作者：
Ghafarzadeh, Masoumeh [1 ]
Namdari, Mehrdad [1 ]
机构：
[1] Lorestan Univ Med Sci, Khorramabad, Iran
来源：
PAKISTAN JOURNAL OF MEDICAL SCIENCES | 2010年 / 26卷 / 02期
关键词：
Soybean; Postmenopausal; SOY PROTEIN; PLASMA-LIPIDS; ISOFLAVONES; MENOPAUSE; BENEFITS; THERAPY; DENSITY; DISEASE; ACID;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background: To investigate the effect of soybean on serum lipids and lipoproteins in hypercholesterolemic postmenopausal women. Methodology: One hundred participants were included and divided randomly into two arms. One arm received two grams of soy every day, while the other group received similar shaped capsules filled with placebo. Subjects and outcome assessors were kept blind to the contents of the capsules. Serum cholesterol, triglyceride and low- and high-density lipoproteins were measured before and after the intervention. Results: The two groups were similar in their baseline characteristics. We observed no favorable changes in lipid profile in either of the two groups. The two arms of the study responded similarly to the intervention and no statistically significant difference was observed between these responses. Conclusion: This double-blind randomized controlled trial does not support the hypothesis that the use of soybean improves serum lipid constituents in postmenopausal women having hypercholesterolemia.
引用
收藏
页码：407 / 410
页数：4
相关论文
共 15 条
[1]  
BEAGLEHOLE R, 1990, EPIDEMIOL REV, V12, P1
[2]   Soy protein intake by perimenopausal women does not affect circulating lipids and lipoproteins or coagulation and fibrinolytic factors [J].
Dent, SB ;
Peterson, CT ;
Brace, LD ;
Swain, JH ;
Reddy, MB ;
Hanson, KB ;
Robinson, JG ;
Alekel, DL .
JOURNAL OF NUTRITION, 2001, 131 (09) :2280-2287
[3]   Effects of soybean protein and very low dietary cholesterol on serum lipids, biliary lipids, and fecal sterols in humans [J].
Duane, WC .
METABOLISM-CLINICAL AND EXPERIMENTAL, 1999, 48 (04) :489-494
[4]  
Engelman HM, 2005, AM J CLIN NUTR, V81, P590
[5]   HORMONE-THERAPY TO PREVENT DISEASE AND PROLONG LIFE IN POSTMENOPAUSAL WOMEN [J].
GRADY, D ;
RUBIN, SM ;
PETITTI, DB ;
FOX, CS ;
BLACK, D ;
ETTINGER, B ;
ERNSTER, VL ;
CUMMINGS, SR .
ANNALS OF INTERNAL MEDICINE, 1992, 117 (12) :1016-1037
[6]  
Hsu CS, 2001, J REPROD MED, V46, P221
[7]   Development of a soy food frequency questionnaire to estimate isoflavone consumption in US adults [J].
Kirk, P ;
Patterson, RE ;
Lampe, J .
JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION, 1999, 99 (05) :558-563
[8]   Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women - A randomized controlled trial [J].
Kreijkamp-Kaspers, S ;
Kok, L ;
Grobbee, DE ;
de Haan, EHF ;
Aleman, A ;
Lampe, JW ;
van der Schouw, YT .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (01) :65-74
[9]  
Maturana MA, 2007, CLINICS, V62, P77, DOI 10.1590/S1807-59322007000100012
[10]   Effects of soybean D-LeciVita product on serum lipids and fatty acid composition in type 2 diabetic patients with hyperlipidemia [J].
Medic, Danijela Ristic ;
Ristic, Vanja ;
Arsic, Aleksandra ;
Postic, Marija ;
Ristic, Gordana ;
Mladenovic, Vera Blazencic ;
Tepsic, Jasna .
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2006, 16 (06) :395-404
12