Passiflora tenuifila Killip: Assessment of chemical composition by 1H NMR and UPLC-ESI-Q-TOF-MSE and its bioactive properties in a rotenone-induced rat model of Parkinson's disease

被引：3

作者：

Rodrigues Holanda, Dayse Karine ^{[1
]}

Wurlitzer, Nedio Jair ^{[2
]}

Dionisio, Ana Paula ^{[2
]}

Campos, Adriana Rolim ^{[4
]}

de Brito, Edy Sousa ^{[2
]}

Alexandre e Silva, Lorena Mara ^{[2
]}

Vasconcelos Ribeiro, Paulo Riceli ^{[2
]}

Costa, Ana Maria ^{[3
]}

Machado de Souza, Paulo Henrique ^{[1
]}

Viana Lima, Francisco Arnaldo ^{[5
]}

Moreira, Renato de Azevedo ^{[4
]}

机构：

[1] Univ Fed Ceara, Dept Food Engn, Fortaleza, Ceara, Brazil

[2] Embrapa Agroind Trop, Dra Sara Mesquita 2270, BR-60511110 Fortaleza, Ceara, Brazil

[3] Embrapa Cerrados, Brasilia, DF, Brazil

[4] UNIFOR Univ Fortaleza, Fortaleza, CE, Brazil

[5] Univ Fed Ceara, Dept Fisiol & Farmacol, Fortaleza, Ceara, Brazil

来源：

JOURNAL OF FUNCTIONAL FOODS | 2019年 / 62卷

关键词：

Parkinsonism induced model; Garlic passion fruit; Antioxidant; Phenolic compounds; ANTIOXIDANT ACTIVITY; ANXIOLYTIC ACTIVITY; PASSION-FRUIT; OPEN-FIELD; APIGENIN; MICE; POLYPHENOLS; INVOLVEMENT; MODULATION; FLAVONOIDS;

D O I：

10.1016/j.jff.2019.103529

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Passiflora tenuifila Killip is a wild species, with no studies regarding to functional properties. The objective of this work was to evaluate the chemical composition, including NMR and UPLC, toxicity and functional effect in a Parkinsonism model. The fruits (peel, pulp, and seed) were crushed, lyophilized and characterized. The subchronic toxicity was evaluated in Wistar rats during 90 days, and the Parkinsonism symptoms were induced by rotenone and after treated with P. tenuifila daily doses during 21 days. Composition results indicated a high total dietary fiber content, total polyphenols, and antioxidant activity. The subchronic toxicity results showed that garlic passion fruit did not present signs of toxicity. In the Parkinsonism model, the tests allow to indicate that the consumption of garlic passion fruit causes an improvement and possible effect of recovery of the damages induced by the rotenone, being these effects of improvement proportional to the consumption.

引用

页数：9

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