Synthesis of [3-[2-(dimethylamino)ethyl]-2[[3-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1H-indol-5-yl]-N-methylmethanesulfonamide -: the main sumatriptane impurity

被引：0
|
作者：
Skwierawska, A [1 ]
Paluszkiewicz, E [1 ]
机构：
[1] Gdansk Tech Univ, Dept Chem, PL-80952 Gdansk, Poland
来源：
POLISH JOURNAL OF CHEMISTRY | 2003年 / 77卷 / 03期
关键词：
indole derivatives; sumatriptane; drug impurities;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Alkylation of sumatriptane in position 2 by 3-[2-(dimethylamino)ethyl]-5-indolemethanol has been described. Alternative multistep synthesis of 3-[2-(dimethylamino)ethyl]5-indolemethanol has been presented.
引用
收藏
页码：329 / 332
页数：4
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