Novel and facile synthesis of pyrazolo[3,4-d]pyrimidines

被引：0

作者：

Abu Elmaati, TM ^{[1
]}

机构：

[1] Fac Specif Educ, New Damietta, Egypt

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2002年 / 57卷 / 11期

关键词：

6-hydrazinopyrimidine; pyrazolo[3,4-d]pyrimidine;

D O I：

暂无

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The reaction of 6-hydrazinopyrimidine-2,4-dione derivative 1 with alkyl or aryl isocyanates 2a-d resulted in a novel and facile synthesis of pyrazolo[3,4-d]pyrimidine derivative 5a-d in good yield.

引用

页码：1333 / 1335

页数：3

共 25 条

[1] BENNETT LL, 1969, BIOCHEM PHARMACOL, V18, P725
[2] Studies on uracils:: an efficient method for the synthesis of novel 1-allyl-6-(1′,2′,3′-triazolyl) analogues of HEPT
Bhuyan, PJ
Borah, HN
Sandhu, JS
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1999, (21): : 3083 - 3084
[3] 5-SUBSTITUTED PYRIMIDINE NUCLEOSIDES AND NUCLEOTIDES
BRADSHAW, TK
HUTCHINSON, DW
[J]. CHEMICAL SOCIETY REVIEWS, 1977, 6 (01) : 43 - 62
[4] Brown D. J., 1984, Comprehensive Heterocyclic Chemistry, V1, P57
[5] DECLERCQ E, 1987, J BIOL CHEM, V262, P14905
[6] POTENTIATION BY INHIBITION OF DRUG DEGRADATION - 6-SUBSTITUTED PURINES AND XANTHINE OXIDASE
ELION, GB
RUNDLES, RW
NATHAN, H
CALLAHAN, S
HITCHINGS, GH
BIEBER, S
[J]. BIOCHEMICAL PHARMACOLOGY, 1963, 12 (01) : 85 - &
[7] ELION GB, 1987, EXP PHARM, V51, P48
[8] FYFE JA, 1973, J BIOL CHEM, V248, P3801
[9] 2'-FLUORINATED ARABINONUCLEOSIDES OF 5-(2-HALOALKYL)URACIL - SYNTHESIS AND ANTIVIRAL ACTIVITY
GRIENGL, H
WANEK, E
SCHWARZ, W
STREICHER, W
ROSENWIRTH, B
DECLERCQ, E
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (07) : 1199 - 1204
[10] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF PYRAZOLO[3,4-D]PYRIMIDINE NUCLEOSIDES AND NUCLEOTIDES RELATED TO TUBERCIDIN, TOYOCAMYCIN, AND SANGIVAMYCIN
HECHT, SM
FRYE, RB
WERNER, D
FUKUI, T
HAWRELAK, SD
[J]. BIOCHEMISTRY, 1976, 15 (05) : 1005 - 1015

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