Biomarkers of Disease Activity, Cure, and Relapse in Tuberculosis

被引：17

作者：

Doherty, T. Mark ^{[1
]}

Wallis, Robert S. ^{[2
]}

Zumla, Alimuddin ^{[3
]}

机构：

[1] Statens Serum Inst, Dept Infect Dis Immunol, DK-2300 Copenhagen S, Denmark

[2] Pfizer Global Res & Dev, New London, CT 06320 USA

[3] UCL, Sch Med, London W1N 8AA, England

来源：

CLINICS IN CHEST MEDICINE | 2009年 / 30卷 / 04期

关键词：

Tuberculosis; Diagnosis; Biomarkers; TUMOR-NECROSIS-FACTOR; REGULATORY T-CELLS; INTERFERON-GAMMA PRODUCTION; GROWTH-FACTOR-BETA; MYCOBACTERIUM-TUBERCULOSIS; LATENT TUBERCULOSIS; PULMONARY TUBERCULOSIS; MESSENGER-RNA; SKIN-TEST; IFN-GAMMA;

D O I：

10.1016/j.ccm.2009.08.008

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The changing face of tuberculosis, with epidemics fueled by HIV and urbanization in much of the world and a relative increase in the importance of latent tuberculosis as a source of cases in the more economically developed countries, has led to a demand for more robust, clinically applicable diagnostic tools. As a result, research aiming to identify biomarkers of Mycobacterium tuberculosis infection and disease has flourished. This article discusses the most recent findings of that work.

引用

页码：783 / +

页数：15

共 143 条

[1] Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum [J].

Agranoff, Dan ;

Fernandez-Reyes, Delmiro ;

Papadopoulos, Marios C. ;

Rojas, Sergio A. ;

Herbster, Mark ;

Loosemore, Alison ;

Tarelli, Edward ;

Sheldon, Jo ;

Schwenk, Achim ;

Pollak, Richard ;

Rayner, Charlotte F. J. ;

Krishna, Sarjeev .

LANCET, 2006, 368 (9540) :1012-1021

[2] The prognosis of latent tuberculosis: can disease be predicted [J].

Andersen, Peter ;

Doherty, T. Mark ;

Pai, Madhukar ;

Weldingh, Karin .

TRENDS IN MOLECULAR MEDICINE, 2007, 13 (05) :175-182

[3]

[Anonymous], 2009, GLOBAL TUBERCULOSIS

[4] Double-blind randomized Phase I study comparing rdESAT-6 to tuberculin as skin test reagent in the diagnosis of tuberculosis infection [J].

Arend, Sandra M. ;

Franken, Willeke P. J. ;

Aggerbeck, Henrik ;

Prins, Corine ;

van Dissel, Jaap T. ;

Thierry-Carstensen, Birgit ;

Tingskov, Pernille Nyholm ;

Weldingh, Karin ;

Andersen, Peter .

TUBERCULOSIS, 2008, 88 (03) :249-261

[5] Application of a circulating antigen detection immunoassay for laboratory diagnosis of extra-pulmonary and pulmonary tuberculosis [J].

Attallah, AM ;

Osman, S ;

Saad, A ;

Omran, M ;

Ismail, H ;

Ibrahim, G ;

Abo-Naglla, A .

CLINICA CHIMICA ACTA, 2005, 356 (1-2) :58-66

[6] Bioactivation of latent transforming growth factor β1 by Mycobacterium tuberculosis in human mononuclear phagocytes [J].

Aung, H ;

Wu, M ;

Johnson, JL ;

Hirsch, CS ;

Toossi, Z .

SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2005, 61 (06) :558-565

[7] Rapid and Specific Diagnosis of Tuberculous Pleuritis With Immunohistochemistry by Detecting Mycobacterium Tuberculosis Complex Specific Antigen MPT64 in Patients From a HIV Endemic Area [J].

Baba, Kamaldeen ;

Dyrhol-Riise, Anne Margarita ;

Sviland, Lisbet ;

Langeland, Nina ;

Hoosen, Anwar A. ;

Wiker, Harald G. ;

Mustafa, Tehmina .

APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2008, 16 (06) :554-561

[8] Antigens secreted from Mycobacterium tuberculosis:: Identification by proteomics approach and test for diagnostic marker [J].

Bahk, YY ;

Kim, SA ;

Kim, JS ;

Euh, HJ ;

Bai, GH ;

Cho, SN ;

Kim, YS .

PROTEOMICS, 2004, 4 (11) :3299-3307

[9]

BAJAJ G, 1989, Indian Pediatrics, V26, P1010

[10]

Balcewicz-Sablinska MK, 1998, J IMMUNOL, V161, P2636

← 1 2 3 4 5 6 7 8 9 10 →