Biomarkers of Disease Activity, Cure, and Relapse in Tuberculosis

被引：17

作者：

Doherty, T. Mark ^{[1
]}

Wallis, Robert S. ^{[2
]}

Zumla, Alimuddin ^{[3
]}

机构：

[1] Statens Serum Inst, Dept Infect Dis Immunol, DK-2300 Copenhagen S, Denmark

[2] Pfizer Global Res & Dev, New London, CT 06320 USA

[3] UCL, Sch Med, London W1N 8AA, England

来源：

CLINICS IN CHEST MEDICINE | 2009年 / 30卷 / 04期

关键词：

Tuberculosis; Diagnosis; Biomarkers; TUMOR-NECROSIS-FACTOR; REGULATORY T-CELLS; INTERFERON-GAMMA PRODUCTION; GROWTH-FACTOR-BETA; MYCOBACTERIUM-TUBERCULOSIS; LATENT TUBERCULOSIS; PULMONARY TUBERCULOSIS; MESSENGER-RNA; SKIN-TEST; IFN-GAMMA;

D O I：

10.1016/j.ccm.2009.08.008

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The changing face of tuberculosis, with epidemics fueled by HIV and urbanization in much of the world and a relative increase in the importance of latent tuberculosis as a source of cases in the more economically developed countries, has led to a demand for more robust, clinically applicable diagnostic tools. As a result, research aiming to identify biomarkers of Mycobacterium tuberculosis infection and disease has flourished. This article discusses the most recent findings of that work.

引用

页码：783 / +

页数：15

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