TIMP-1 INHIBITS PANCREATIC STELLATE CELL APOPTOSIS: IMPLICATIONS FOR PANCREATIC FIBROSIS

被引:0
|
作者
Patel, M. [1 ]
Collins, J. E. [1 ]
Fowell, A. J. [1 ]
Benyon, R. C. [1 ]
Fine, D. R. [1 ]
机构
[1] Univ Southampton, Pancreat Res Grp, Southampton, Hants, England
关键词
D O I
10.1136/gut.2009.209072k
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:A80 / A80
页数:1
相关论文
共 50 条
  • [41] MMP-2 and TIMP-1 are derived from, not in response to, pancreatic cancer
    Bloomston, M
    Shafii, A
    Zervos, EE
    Rojiani, A
    Rosemurgy, AS
    JOURNAL OF SURGICAL RESEARCH, 2002, 102 (01) : 35 - 38
  • [42] Pancreatic stellate cells are activated in human and experimental pancreatic fibrosis.
    Haber, P
    Keogh, G
    Apte, M
    Moran, C
    Pirola, R
    McCaughan, G
    Korsten, M
    Wilson, J
    GASTROENTEROLOGY, 1998, 114 (04) : A466 - A466
  • [43] The pancreatic stellate cell: a star on the rise in pancreatic diseases
    Omary, M. Bishr
    Lugea, Aurelia
    Lowe, Anson W.
    Pandol, Stephen J.
    JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (01): : 50 - 59
  • [44] Silencing timps with sirna: defining a role for TIMP-1 in hepatic stellate cell proliferation
    Fowell, A. J.
    Rosenberg, W. M. C.
    Benyon, R. C.
    GUT, 2008, 57 : A40 - A40
  • [45] A nanodrug simultaneously inhibits pancreatic stellate cell activation and regulatory T cell infiltration to promote the immunotherapy of pancreatic cancer
    Wang, Rongze
    Hong, Keze
    Zhang, Qiaoyun
    Cao, Jianrong
    Huang, Tao
    Xiao, Zecong
    Wang, Yong
    Shuai, Xintao
    ACTA BIOMATERIALIA, 2023, 169 : 451 - 463
  • [46] Apoptosis in activated rat pancreatic stellate cells
    Klonowski-Stumpe, H
    Fischer, R
    Reinehr, R
    Lüthen, R
    Häussinger, D
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2002, 283 (03): : G819 - G826
  • [47] HEPATIC LIPOCYTES, TIMP-1 AND LIVER FIBROSIS
    ARTHUR, MJP
    IREDALE, JP
    JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF LONDON, 1994, 28 (03): : 200 - 208
  • [48] TIMP-1 antisense gene transfection attenuates the invasive potential of pancreatic cancer cells in vitro and inhibits tumor growth in vivo
    Bloomston, M
    Shaffi, A
    Zervos, E
    Rosemurgy, AS
    AMERICAN JOURNAL OF SURGERY, 2005, 189 (06): : 675 - 679
  • [49] What's new in alcoholic pancreatic fibrosis: Role of pancreatic stellate cells
    Apte, Minoti V.
    Pirola, Ron C.
    Wilson, Jeremy S.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2006, 30 (09) : 113A - 113A
  • [50] Urinary TIMP-1 and MMP-2 levels detect the presence of pancreatic malignancies
    Roy, R.
    Zurakowski, D.
    Wischhusen, J.
    Frauenhoffer, C.
    Hooshmand, S.
    Kulke, M.
    Moses, M. A.
    BRITISH JOURNAL OF CANCER, 2014, 111 (09) : 1772 - 1779