Imported case of Dengue virus 3 genotype I in Rio de Janeiro state, Brazil

被引:1
|
作者
Lima de Mendonca, Marcos Cesar [1 ]
Mares-Guia, Maria Angelica [1 ]
dos Santos Rodrigues, Cintia Damasceno [1 ]
dos Santos, Carolina Cardoso [1 ]
Levy Chalhoub, Flavia Lowen [1 ]
Machado Araujo, Eliane Saraiva [1 ]
Chieppe, Alexandre Otavio [2 ]
Ribeiro Nogueira, Rita Maria [1 ]
Bispo de Filippis, Ana Maria [1 ]
机构
[1] Inst Oswaldo Cruz, Lab Flavivirus, Fundacao Oswald Cruz Fiocruz, Rio De Janeiro, RJ, Brazil
[2] Secretaria Estado Saude Rio de Janeiro, Rio De Janeiro, RJ, Brazil
来源
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2018年 / 113卷 / 08期
关键词
dengue; sequencing; genotyping; EPIDEMIOLOGY;
D O I
10.1590/0074-02760180036
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The dengue virus (DENV), of the genus Flavivirus (Flaviviridae), has four antigenically distinct serotypes, of which DENV-3 is classified into five genotypes. Here, we describe the detection of DENV-3 genotype I in sera of a Brazilian patient travelling from Singapore to Rio de Janeiro, Brazil, by using multiplex real-time RT-PCR, DNA sequencing of the whole envelope protein gene, and phylogenetic analysis. The virus shares ancestry with those identified in Bali, Indonesia, in 2015. It is possible that arboviruses such as Chikungunya ECSA genotype, DENV-4 genotype I, and Zika were introduced in Brazil from other continents during the multiple international events hosted by the country over the last four years, including World Youth Day, the Soccer World Cup, and the Summer Olympics.
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页数:3
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