Clinical features of scleroderma patients with contracture of phalanges

被引:10
作者
Ashida, Ryuichi
Ihn, Hironobu
Mimura, Yoshihiro
Jinnin, Masatoshi
Asano, Yoshihide
Kubo, Masahide
Tamaki, Kunihiko
机构
[1] Kumamoto Univ, Fac Med & Pharmaceut Sci, Dept Dermatol & Plast & Reconstruct Surg, Kumamoto 8608556, Japan
[2] Univ Tokyo, Fac Med, Dept Dermatol, Tokyo 113, Japan
[3] Int Univ Hlth & Welf, Mita Hosp, Dept Dermatol, Tokyo, Japan
关键词
heart involvement; oesophageal involvement; pulmonary fibrosis;
D O I
10.1007/s10067-006-0490-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Contracture of phalanges (CP) is a frequent complication of patients with systemic sclerosis (SSc). The objective of this study was to examine the prevalance of CP in patients with SSc and investigate the clinical and laboratory features of SSc patients with CP. Three hundred and fifty patients with SSc were examined. CP was found in 164 of the 350 patients (47%) with SSc. The prevalence of oesophageal involvement, pulmonary fibrosis or heart involvement was significantly greater in the patients with CP than that in those without CP. Our study suggested that the presence of CP may be a marker of oesophageal involvement, pulmonary fibrosis and heart involvement.
引用
收藏
页码:1275 / 1277
页数:3
相关论文
共 14 条
[1]  
CLARK JA, 1971, MAYO CLIN PROC, V46, P97
[2]   Measurement of anticardiolipin antibodies by ELISA using beta(2)-glycoprotein I (beta(2)-GPI) in systemic sclerosis [J].
Ihn, H ;
Sato, S ;
Fujimoto, M ;
Kikuchi, K ;
Igarashi, A ;
Soma, Y ;
Tamaki, K ;
Takehara, K .
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 1996, 105 (03) :475-479
[3]  
Ihn H, 1999, CLIN EXP IMMUNOL, V117, P383
[4]  
LEROY EC, 1988, J RHEUMATOL, V15, P202
[5]   Clinical and laboratory features of scleroderma patients developing skeletal myopathy [J].
Mimura, Y ;
Ihn, H ;
Jinnin, M ;
Asano, Y ;
Yamane, K ;
Tamaki, K .
CLINICAL RHEUMATOLOGY, 2005, 24 (02) :99-102
[6]   ANTIHISTONE ANTIBODIES IN SYSTEMIC-SCLEROSIS - ASSOCIATION WITH PULMONARY FIBROSIS [J].
SATO, S ;
IHN, H ;
KIKUCHI, K ;
TAKEHARA, K .
ARTHRITIS AND RHEUMATISM, 1994, 37 (03) :391-394
[7]   ANTINUCLEAR ANTIBODIES AND ANTI-DNA ANTIBODIES IN SCLERODERMA - A POSSIBLE RELATIONSHIP BETWEEN JOINT MANIFESTATIONS AND INCREASED ANTIBODIES IN LOCALIZED SCLERODERMA [J].
SERUP, J ;
STAUNOLSEN, P .
ALLERGY, 1986, 41 (06) :452-456
[8]   HIGH TITERS OF AUTOANTIBODIES TO TOPOISOMERASE-I (SCL-70) IN SERA FROM SCLERODERMA PATIENTS [J].
SHERO, JH ;
BORDWELL, B ;
ROTHFIELD, NF ;
EARNSHAW, WC .
SCIENCE, 1986, 231 (4739) :737-740
[9]   CLINICAL CORRELATIONS AND PROGNOSIS BASED ON SERUM AUTOANTIBODIES IN PATIENTS WITH SYSTEMIC-SCLEROSIS [J].
STEEN, VD ;
POWELL, DL ;
MEDSGER, TA .
ARTHRITIS AND RHEUMATISM, 1988, 31 (02) :196-203
[10]   CLINICAL AND LABORATORY ASSOCIATIONS OF ANTICENTROMERE ANTIBODY IN PATIENTS WITH PROGRESSIVE SYSTEMIC-SCLEROSIS [J].
STEEN, VD ;
ZIEGLER, GL ;
RODNAN, GP ;
MEDSGER, TA .
ARTHRITIS AND RHEUMATISM, 1984, 27 (02) :125-131