Pandemic potential of avian influenza A (H7N9) viruses

被引：102
|
作者：
Watanabe, Tokiko [1 ,2 ,3 ]
Watanabe, Shinji [2 ,4 ]
Maher, Eileen A. [1 ]
Neumann, Gabriele [1 ]
Kawaoka, Yoshihiro [1 ,2 ,3 ,5 ]
机构：
[1] Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, Madison, WI 53711 USA
[2] Japan Sci & Technol Agcy, ERATO Infect Induced Host Responses Project, Kawaguchi, Saitama 3320012, Japan
[3] Univ Tokyo, Inst Med Sci, Div Virol, Dept Microbiol & Immunol, Tokyo 1088639, Japan
[4] Miyazaki Univ, Lab Vet Microbiol, Dept Vet Sci, Miyazaki 8892192, Japan
[5] Univ Tokyo, Dept Special Pathogens, Int Res Ctr Infect Dis, Inst Med Sci, Tokyo 1088639, Japan
来源：
TRENDS IN MICROBIOLOGY | 2014年 / 22卷 / 11期
基金：
日本科学技术振兴机构;
关键词：
avian influenza H7N9 viruses; transmission; pandemic potential; AMINO-ACID SUBSTITUTIONS; HOST-RANGE DETERMINANTS; TO-PERSON TRANSMISSION; A(H7N9) VIRUS; HUMAN INFECTION; RECEPTOR-BINDING; CLINICAL FINDINGS; JIANGSU PROVINCE; MOLECULAR-BASIS; CHINA;
D O I：
10.1016/j.tim.2014.08.008
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Avian influenza viruses rarely infect humans, but the recently emerged avian H7N9 influenza viruses have caused sporadic infections in humans in China, resulting in 440 confirmed cases with 122 fatalities as of 16 May 2014. In addition, epidemiologic surveys suggest that there have been asymptomatic or mild human infections with H7N9 viruses. These viruses replicate efficiently in mammals, show limited transmissibility in ferrets and guinea pigs, and possess mammalian-adapting amino acid changes that likely contribute to their ability to infect mammals. In this review, we summarize the characteristic features of the novel H7N9 viruses and assess their pandemic potential.
引用
收藏
页码：623 / 631
页数：9
相关论文
共 50 条
  • [21] Tropism of H7N9 influenza viruses in the human respiratory tract
    Belser, Jessica A.
    Tumpey, Terrence M.
    LANCET RESPIRATORY MEDICINE, 2013, 1 (07) : 501 - 502
  • [22] Avian influenza A (H7N9) virus infection in humans: Epidemiology, evolution, and pathogenesis
    Husain, Matloob
    INFECTION GENETICS AND EVOLUTION, 2014, 28 : 304 - 312
  • [23] Evolution of H7N9 highly pathogenic avian influenza virus in the context of vaccination
    Hou, Yujie
    Deng, Guohua
    Cui, Pengfei
    Zeng, Xianying
    Li, Bin
    Wang, Dongxue
    He, Xinwen
    Yan, Cheng
    Zhang, Yaping
    Li, Jiongjie
    Ma, Jinming
    Li, Yanbing
    Wang, Xiurong
    Tian, Guobin
    Kong, Huihui
    Tang, Lijie
    Suzuki, Yasuo
    Shi, Jianzhong
    Chen, Hualan
    EMERGING MICROBES & INFECTIONS, 2024, 13 (01)
  • [24] Characterization of H7N9 influenza A viruses isolated from humans
    Watanabe, Tokiko
    Kiso, Maki
    Fukuyama, Satoshi
    Nakajima, Noriko
    Imai, Masaki
    Yamada, Shinya
    Murakami, Shin
    Yamayoshi, Seiya
    Iwatsuki-Horimoto, Kiyoko
    Sakoda, Yoshihiro
    Takashita, Emi
    McBride, Ryan
    Noda, Takeshi
    Hatta, Masato
    Imai, Hirotaka
    Zhao, Dongming
    Kishida, Noriko
    Shirakura, Masayuki
    de Vries, Robert P.
    Shichinohe, Shintaro
    Okamatsu, Masatoshi
    Tamura, Tomokazu
    Tomita, Yuriko
    Fujimoto, Naomi
    Goto, Kazue
    Katsura, Hiroaki
    Kawakami, Eiryo
    Ishikawa, Izumi
    Watanabe, Shinji
    Ito, Mutsumi
    Sakai-Tagawa, Yuko
    Sugita, Yukihiko
    Uraki, Ryuta
    Yamaji, Reina
    Eisfeld, Amie J.
    Zhong, Gongxun
    Fan, Shufang
    Ping, Jihui
    Maher, Eileen A.
    Hanson, Anthony
    Uchida, Yuko
    Saito, Takehiko
    Ozawa, Makoto
    Neumann, Gabriele
    Kida, Hiroshi
    Odagiri, Takato
    Paulson, James C.
    Hasegawa, Hideki
    Tashiro, Masato
    Kawaoka, Yoshihiro
    NATURE, 2013, 501 (7468) : 551 - +
  • [25] A Closer Look at the Avian Influenza Virus H7N9: A Calm before the Storm?
    Nakhaie, Mohsen
    Rukerd, Mohammad Rezaei Zadeh
    Shahpar, Amirhossein
    Pardeshenas, Mohammad
    Khoshnazar, Seyedeh Mahdieh
    Khazaeli, Mana
    Bashash, Davood
    Nezhad, Nazanin Zeinali
    Charostad, Javad
    JOURNAL OF MEDICAL VIROLOGY, 2024, 96 (11)
  • [26] Comprehensive sequence analysis of HA protein of H7 subtype avian influenza viruses: an emphasis on mutations in novel H7N9 viruses
    Pasricha, Gunisha
    Mukherjee, Sanjay
    Chakrabarti, Alok K.
    FUTURE VIROLOGY, 2014, 9 (03) : 251 - 273
  • [27] Did the Highly Pathogenic Avian Influenza A(H7N9) Viruses Emerged in China Raise Increased Threat to Public Health?
    Zhu, Wenfei
    Yang, Lei
    Shu, Yuelong
    VECTOR-BORNE AND ZOONOTIC DISEASES, 2019, 19 (01) : 22 - 25
  • [28] Comparative Pathogenicity and Transmissibility of Pandemic H1N1, Avian H5N1, and Human H7N9 Influenza Viruses in Tree Shrews
    Xu, Shuai
    Li, Xuyong
    Yang, Jiayun
    Wang, Zhengxiang
    Jia, Yane
    Han, Lu
    Wang, Liang
    Zhu, Qiyun
    FRONTIERS IN MICROBIOLOGY, 2019, 10
  • [29] HUMAN INFECTION WITH AVIAN INFLUENZA A (H7N9) VIRUS
    Zhang, Yi
    Yu, Yong-Sheng
    Chen, Xiao-Hua
    Zang, Guo-Qing
    REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO, 2014, 56 (04): : 367 - 368
  • [30] Nosocomial transmission of avian influenza virus A (H7N9)
    van der Sande, Marianne A. B.
    van der Hoek, Wim
    BMJ-BRITISH MEDICAL JOURNAL, 2015, 351
12345