SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NOVEL 4-PHENYLDIAZENYL-4′-[(4-CHLOROBENZYL)OXY]BIPHENYL DERIVATIVES AS ANTIBACTERIAL AGENTS

被引:3
作者
Moanta, Anca [1 ]
机构
[1] Univ Craiova, Fac Exact Sci, Dept Chem, Craiova 200512, Romania
来源
JOURNAL OF THE CHILEAN CHEMICAL SOCIETY | 2014年 / 59卷 / 01期
关键词
antibacterial activity; azomonoether; FTIR spectra; UV-Vis spectra; mass spectra; NMR spectra; CARBON-STEEL SURFACE; AZO DERIVATIVES; ACID; INHIBITOR; ANALOGS; POTENT; DRUG;
D O I
10.4067/S0717-97072014000100007
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of five new 4-phenyldiazenyl-4'-[(4-chlorobenzyl)oxy]biphenyls have been synthesized by condensing different sodium salts of some 4'-phenyldiazenyl-biphenyl-4-ols with 1-chloro-4-(chloromethyl)benzene. These compounds have been characterized by elemental analysis (C, H, N) and electronic, IR, H-1 NMR and mass spectrometry studies. The obtained compounds were assayed for their antibacterial activity against some bacteria by disk diffusion method.
引用
收藏
页码:2275 / 2278
页数:4
相关论文
共 36 条
[1]   Synthesis, spectroscopic thermal and biological activity studies on azo-containing Schiff base dye and its Cobalt(II), Chromium(III) and Strontium(II) complexes [J].
Alghool, Samir ;
Abd El-Halim, Hanan F. ;
Dahshan, A. .
JOURNAL OF MOLECULAR STRUCTURE, 2010, 983 (1-3) :32-38
[2]  
Bailey R R, 1992, Int J Antimicrob Agents, V2, P19, DOI 10.1016/0924-8579(92)90023-K
[3]   Oxazolidinones: activity, mode of action, and mechanism of resistance [J].
Bozdogan, B ;
Appelbaum, PC .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2004, 23 (02) :113-119
[4]  
Bratulescu G, 2000, REV ROUM CHIM, V45, P277
[5]   RETRACTED: Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrug of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease (Retracted article. See vol. 43, pg. 2909, 2008) [J].
Dhaneshwar, Suneela S. ;
Kandpal, Mini ;
Vadnerkar, Gaurav ;
Rathi, Badal ;
Kadam, S. S. .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 42 (06) :885-890
[6]   Do we still need the aminoglycosides? [J].
Durante-Mangoni, Emanuele ;
Grammatikos, Alexandros ;
Utili, Riccardo ;
Falagas, Matthew E. .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2009, 33 (03) :201-205
[7]   Effect of synthetic lipopeptides formulated in liposomes on the maturation of human dendritic cells [J].
Espuelas, S ;
Roth, A ;
Thumann, C ;
Frisch, B ;
Schuber, F .
MOLECULAR IMMUNOLOGY, 2005, 42 (06) :721-729
[8]  
Gamovskii A. D., 2010, RUSS J COORD CHEM, V36, P479
[9]  
Gaurav Kumar Gaurav Kumar, 2010, Journal of Pharmacy Research, V3, P539
[10]   Macrolides beyond the conventional antimicrobials: a class of potent immunomodulators [J].
Giamarellos-Bourboulis, Evangelos J. .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2008, 31 (01) :12-20