Management of Patients with Patent Foramen Ovale and Cryptogenic Stroke: An Update

被引：34

作者：

Abdelghani, Mohammad ^{[1
,2
,3
]}

El-Shedoudy, Sahar A. O. ^{[4
]}

Nassif, Martina ^{[2
]}

Bouma, Berto J. ^{[2
]}

de Winter, Robbert J. ^{[2
]}

机构：

[1] Segeberger Kliniken, Heart Ctr, Kurpk 1, DE-23795 Bad Segeberg, Germany

[2] Acad Med Ctr, Dept Cardiol, Amsterdam, Netherlands

[3] Al Azhar Univ, Dept Cardiol, Cairo, Egypt

[4] Tanta Univ, Dept Cardiol, Tanta, Egypt

来源：

CARDIOLOGY | 2019年 / 143卷 / 1-2期

关键词：

Patent foramen ovale; Percutaneous closure; Transcatheter closure; Cryptogenic stroke; MEDICAL THERAPY; SEPTAL POUCH; TRANSCATHETER CLOSURE; PERCUTANEOUS CLOSURE; CEREBRAL-ISCHEMIA; RECURRENT STROKE; LEFT ATRIUM; TRANSCRANIAL DOPPLER; ANTIPLATELET THERAPY; ROPE SCORE;

D O I：

10.1159/000501028

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Patent foramen ovale (PFO) is a common benign finding in healthy subjects, but its prevalence is higher in patients with stroke of unclear cause (cryptogenic stroke). PFO is believed to be associated with stroke through paradoxical embolism, and certain clinical and anatomical criteria seem to increase the likelihood of a PFO to be pathological. Recent trials have shown that closure of PFO, especially if associated with an atrial septal aneurysm and/or a large interatrial shunt, may reduce the risk of recurrent stroke as compared to medical treatment. However, it remains challenging to risk stratify patients with suspected PFO-related stroke and to decide if device closure is indicated. We sought to review contemporary evidence and to conclude an evidence-based strategy to prevent recurrence of PFO-related stroke. (c) 2019 S. Karger AG, Basel

引用

页码：62 / 72

页数：11

共 69 条

[1] Meta-Analysis of Transcatheter Closure Versus Medical Therapy for Patent Foramen Ovale in Prevention of Recurrent Neurological Events After Presumed Paradoxical Embolism [J].