Synthesis and antimicrobial evaluation of 4-(1H-benzimidazol-2-yl)-N-[(1H-1,2,3-benzotriazol-1-yl) substituted phenylmethyl] amines

被引：0

作者：

Bhaskar, V. H. ^{[1
]}

Kumar, T. Anil ^{[1
]}

Kumar, M. ^{[1
]}

Jayakar, B. ^{[1
]}

机构：

[1] Deemed Univ, Dept Pharmaceut Chem, Fac Pharm, Vinayaka Missions Res Fdn, Yercaud Adivaram 636008, Salem, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 16卷 / 03期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Some 4-(1H-benzimidazol-2-yl)-N-[(1H-1,2,3-benzotriazol-1-yl) substituted phenylmethyl amines (3a-e) have been obtained by refluxing 4-{[1H-1,2,3-benzotriazol-1-yl (substituted phenyl) methyl] amino benzoic acids (2a-e) with o-phenylenediamine in anhyd pyridine under anhyd condition. 4{[1H-1,2,3-Benzotriazol-1-yl (substituted phenyl) methyl] amino benzoic acids (2a-e) on the other hand have been obtained by the reaction of benzotriazole, p-aminobenzoic acid and various aromatic aldehydes in ethanol. The structures of the synthesized compounds have been characterized by IR and H-1 NMR spectral and elemental data. The title compounds were evaluated for their antibacterial and antifungal activities and found to exhibit a variable degree of activity.

引用

页码：297 / 298

页数：2