New oleanane-type triterpene saponins from Millettia speciosa

被引:2
|
作者
Uchiyama, T
Furukawa, M
Isobe, S
Makino, M
Akiyama, T
Koyama, T
Fujimoto, Y
机构
[1] Nihon Univ, Coll Pharm, Funabashi, Chiba 2748555, Japan
[2] Sankyo Res Lab, Tokyo 1408710, Japan
[3] Nihon Univ, Coll Bioresource Sci, Fujisawa, Kanagawa 2528510, Japan
关键词
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The 70% ethanol extract of the roots of Millettia speciosa gave two new oleanane-type saponins along with two known pterocarpans, medicarpin and maackiain. The structures of new compounds were established on the basis of chemical and spectroscopic evidences. Medicarpin and maackiain showed cytotoxicity against leukemia cells (HL-60) and inhibited leukotrine secretion from RBL-2H3 cells.
引用
收藏
页码:655 / +
页数:8
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