The properties of the sonochemically functionalized nonsteroidal anti-inflammatory drug ketorolac in an Fe3O4-graphene oxide nanocomposite

被引:4
|
作者
Fiadosenka, Uladzimir [1 ]
Matsukovich, Anna [2 ]
Tabulina, Ljudmila [1 ]
Labunov, Vladimir [1 ]
Radziuk, Darya [1 ]
机构
[1] Belarusian State Univ Informat & Radioelect, Lab Integrated Micro & Nanosyst, P Brovki Str 6, Minsk 220013, BELARUS
[2] Natl Acad Sci Belarus, BI Stepanov Inst Phys, Nezavisimosti Ave 68, Minsk 220072, BELARUS
关键词
NANOPARTICLES; FABRICATION; FIELD; ACID;
D O I
10.1039/c9nj03730f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Metallodrugs are in clinical use for the treatment of some diseases. A feasible sonochemical method is described for the complexation of the nonsteroidal anti-inflammatory drug, ketorolac, with an Fe3O4-graphene oxide nanocomposite. The extraction of ketorolac from this nanocomposite was studied in aqueous solutions at pH = 1, 5 and 8, imitating the gastrointestinal medium.
引用
收藏
页码:16118 / 16122
页数:5
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