Hair structures are effectively altered during 810nm diode laser hair epilation at low fluences

Background: Diode lasers with high fluence and cooling technology are effective at removing unwanted hair but are also associated with discomfort and morbidity, especially when treating dark or tanned skins. Methods: Thirty patients with skin phototypes IV and V (range: 23-62 years of age; average: 39years) underwent a single hair removal treatment using a new diode laser (810 nm) technology that incorporates low fluence but very high average power. The treatment technique employed multiple, in-motion, repetitive laser passes on a 100 cm<SU2</SU area of the skin. A 5mm punch biopsy was carried out before and after a single treatment. Tissue samples were harvested and stained with haematoxylin-eosin. Results: The physical integrity of hair follicles was altered with inflammatory infiltrate, hair shaft detachment from its sheath, and perifollicular oedema, related to incipient necrosis. Conclusion: Low fluence but high average power diode laser technology yields significant changes in hair structure and architecture in patients with dark skin types. The procedure caused low levels of discomfort and was well tolerated.</.