Correlating subcortical interhemispheric connectivity and cortical hemispheric dominance in brain tumor patients: A repetitive navigated transcranial magnetic stimulation study

被引:3
作者
Sollmann, Nico [1 ,2 ]
Ille, Sebastian [1 ,2 ]
Tussis, Lorena [1 ,2 ]
Maurer, Stefanie [1 ,2 ]
Hauck, Theresa [1 ,2 ]
Negwer, Chiara [1 ,2 ]
Bauer, Jan S. [3 ]
Ringel, Florian [1 ]
Meyer, Bernhard [1 ]
Krieg, Sandro M. [1 ,2 ]
机构
[1] Tech Univ Munich, Klinikum Rechts Isar, Dept Neurosurg, Ismaninger Str 22, D-81675 Munich, Germany
[2] Tech Univ Munich, Klinikum Rechts Isar, TUM Neuroimaging Ctr, D-81675 Munich, Germany
[3] Tech Univ Munich, Klinikum Rechts Isar, Dept Radiol, Neuroradiol Sect, D-81675 Munich, Germany
关键词
Diffusion tensor imaging; Fiber tracking; Hemispheric dominance; Language; Object naming; Transcranial magnetic stimulation; DTI FIBER TRACKING; CORPUS-CALLOSUM; LANGUAGE LATERALIZATION; CORTICOSPINAL TRACT; NAMING ERRORS; MOTOR CORTEX; BROCAS AREA; TRACTOGRAPHY; SCHIZOPHRENIA; ANATOMY;
D O I
10.1016/j.clineuro.2015.12.010
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: The present study aims to investigate the relationship between transcallosal interhemispheric connectivity (IC) and hemispheric language lateralization by using a novel approach including repetitive navigated transcranial magnetic stimulation (rTMS), hemispheric dominance ratio (HDR) calculation, and rTMS-based diffusion tensor imaging fiber tracking (DTI FT). Methods: 31 patients with left-sided perisylvian brain lesions underwent diffusion tensor imaging (DTI) and rTMS language mapping. Cortical language-positive rTMS spots were used to calculate HDRs (HDR: quotient of the left-sided divided by right-sided naming error rates for corresponding left- and right sided cortical regions) and to create regions of interest (ROIs) for DTI FT. Then, fibers connecting the rTMS-based ROIs of both hemispheres were tracked, and the correlation of IC to HDRs was calculated via Spearman's rank correlation coefficient (r(s)). Results: Fibers connecting rTMS-based ROIs of both hemispheres were detected in 12 patients (38.7%). Within the patients in which IC was detected, the mean number of subcortical IC fibers standard deviation (SD) was 138.0 +/- 346.5 (median: 7.5; range: 1-1,217 fibers). Regarding rs for the correlation of HDRs and fiber numbers of patients that showed IC, only moderate correlation was revealed. Conclusion: Our approach might be beneficial and technically feasible for further investigation of the relationship between IC and language lateralization. However, only moderate correlation was revealed in the present study. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:56 / 64
页数:9
相关论文
共 55 条
  • [1] One hundred million years of interhemispheric communication: the history of the corpus callosum
    Aboitiz, F
    Montiel, J
    [J]. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2003, 36 (04) : 409 - 420
  • [2] FIBER COMPOSITION OF THE HUMAN CORPUS-CALLOSUM
    ABOITIZ, F
    SCHEIBEL, AB
    FISHER, RS
    ZAIDEL, E
    [J]. BRAIN RESEARCH, 1992, 598 (1-2) : 143 - 153
  • [3] Functional hemispheric lateralization for language in patients with schizophrenia
    Alary, Mathieu
    Delcroix, Nicolas
    Leroux, Elise
    Razafimandimby, Annick
    Brazo, Perrine
    Delamillieure, Pascal
    Dollfus, Sonia
    [J]. SCHIZOPHRENIA RESEARCH, 2013, 149 (1-3) : 42 - 47
  • [4] Reduced functional cerebral lateralization: a biomarker of schizophrenia?
    Alary, Mathieu
    Razafimandimby, Annick
    Delcroix, Nicolas
    Leroux, Elise
    Delamillieure, Pascal
    Brazo, Perrine
    Dollfus, Sonia
    [J]. BIPOLAR DISORDERS, 2013, 15 (04) : 449 - 451
  • [5] Motor and language DTI Fiber Tracking combined with intraoperative subcortical mapping for surgical removal of gliomas
    Bello, Lorenzo
    Gambini, Anna
    Castellano, Antonella
    Carrabba, Giorgio
    Acerbi, Francesco
    Fava, Enrica
    Giussani, Carlo
    Cadiolib, Marcello
    Blasi, Valeria
    Casarotti, Alessandra
    Papagno, Costanza
    Gupta, Arun K.
    Gaini, Sergio
    Scotti, Giuseppe
    Falini, Andrea
    [J]. NEUROIMAGE, 2008, 39 (01) : 369 - 382
  • [6] Accuracy of diffusion tensor magnetic resonance imaging tractography assessed using intraoperative subcortical stimulation mapping and magnetic source imaging
    Berman, Jeffrey I.
    Berger, Mitchel S.
    Chung, Sungwon
    Nagarajan, Srikantan S.
    Henry, Roland G.
    [J]. JOURNAL OF NEUROSURGERY, 2007, 107 (03) : 488 - 494
  • [7] A diffusion tensor imaging tractography atlas for virtual in vivo dissections
    Catani, Marco
    Thiebaut de Schotten, Michel
    [J]. CORTEX, 2008, 44 (08) : 1105 - 1132
  • [8] Navigated Transcranial Magnetic Stimulation for "Somatotopic" Tractography of the Corticospinal Tract
    Conti, Alfredo
    Raffa, Giovanni
    Granata, Francesca
    Rizzo, Vincenzo
    Germano, Antonino
    Tomasello, Francesco
    [J]. OPERATIVE NEUROSURGERY, 2014, 10 (04) : 542 - 554
  • [9] Analysis of naming errors during cortical stimulation mapping: Implications for models of language representation
    Corina, David P.
    Loudermilk, Brandon C.
    Detwiler, Landon
    Martin, Richard F.
    Brinkley, James F.
    Ojemann, George
    [J]. BRAIN AND LANGUAGE, 2010, 115 (02) : 101 - 112
  • [10] Dissociation of action and object naming: Evidence from cortical stimulation mapping
    Corina, DP
    Gibson, EK
    Martin, R
    Poliakov, A
    Brinkley, J
    Ojemann, GA
    [J]. HUMAN BRAIN MAPPING, 2005, 24 (01) : 1 - 10