Predictors of Length of Hospital Stay, Mortality, and Outcomes Among Hospitalised COVID-19 Patients in Saudi Arabia: A Cross-Sectional Study

被引:66
作者
Alwafi, Hassan [1 ]
Naser, Abdallah Y. [2 ]
Qanash, Sultan [3 ,4 ]
Brinji, Ahmad S. [5 ]
Ghazawi, Maher A. [5 ]
Alotaibi, Basil [6 ]
Alghamdi, Ahmad [7 ]
Alrhmani, Aisha [7 ]
Fatehaldin, Reham [7 ]
Alelyani, Ali [7 ]
Basfar, Abdulrhman [7 ]
AlBarakati, Abdulaziz [7 ]
Alsharif, Ghaidaa F. [7 ]
Obaid, Elaf F. [7 ]
Shabrawishi, Mohammed [7 ,8 ]
机构
[1] Umm Al Qura Univ, Fac Med, Mecca, Saudi Arabia
[2] Isra Univ, Fac Pharm, Dept Appl Pharmaceut Sci & Clin Pharm, Amman, Jordan
[3] King Saud bin Abdulaziz Univ Hlth Sci, King Abdulaziz Med City, Jeddah, Saudi Arabia
[4] King Abdul Aziz Med City, Dept Internal Med, Natl Guard Hosp, Jeddah, Saudi Arabia
[5] Al Noor Specialist Hosp, Dept Radiol, Mecca, Saudi Arabia
[6] King Saud Univ, Coll Pharm, Riyadh, Saudi Arabia
[7] Al Noor Specialist Hosp, Dept Internal Med, Mecca, Saudi Arabia
[8] Al Noor Specialist Hosp, Dept Resp Med, Mecca 24242, Saudi Arabia
来源
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE | 2021年 / 14卷
关键词
COVID-19; hospitalisation; length of stay; survival; ICU; Saudi Arabia;
D O I
10.2147/JMDH.S304788
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Background: COVID-19 pandemic is a major strain on health and economic systems, with rapidly increasing demand for in patients' facilities. Disease diagnosis and estimating patients at higher risk is important for the optimal management during the pandemic. This study aimed to identify the predictors of mortality and length of hospital stay in COVID-19 patients. Methods: A retrospective cross-sectional study was conducted between March 2020 and August 2020 at Al-Noor Specialist Hospital in Mecca, Saudi Arabia. All patients who were admitted and had a confirmed COVID-19 diagnosis by a real-time polymerase chain reaction (PCR) were included in the study. Descriptive statistics were used to describe patients' demographic characteristics, laboratory findings, and clinical outcomes. Multiple logistic/linear regression analysis was used to identify predictors of death and length of stay at the hospital. Results: A total of 706 patients were hospitalised for COVID-19. The mean age was 48.0 years (SD: 15.6 years). More than half of the patients (68.5%; n= 292) were males. The median duration of stay at the hospital was 6.0 days (IQR: 300-10:00). The prevalence rate of venous thromboembolism (VTE) among the patients was 3.0% (n= 21). In the multivariate logistic regression analysis, age (AOR: 1.05; 1.02-1.09), patients with end-stage renal disease (AOR: 6.44; 2.20-18.87), low Oxygen saturation SPO2 (AOR: 9.92; 4.19-23.50), D.dimer >0.5 (AOR: 13.31; 5.45-32.49), ESR>10 mm/h (AOR: 4.08; 1.72-9.68), Ferritin>400mcg/L (AOR: 18.55; 6.89-49.96), and Procalcitonin>0.5ug/L (AOR: 8.23; 1.81- 37.40) were associated with a higher risk of death among patients with COVID-19. Patients with VTE (AOR: 12.86; 3.07- 53.92) were at higher risk of death due to COVID-19. Conclusion: Hospitalised COVID-19 patients have multiple negative consequences in terms of their laboratory findings, signs and symptoms. Age and end-stage renal diseases have a significant impact on the mortality rate and the length of hospital stay among COVID-19 patients.
引用
收藏
页码:839 / 852
页数:14
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