Synthesis of Functionalized Pyrazolo[1,5-a]pyridines: [3+2]Cycloaddition of N-Aminopyridines and α,β-Unsaturated Carbonyl Compounds/Alkenes at Room Temperature

被引：23

作者：

Ravi, Chitrakar ^{[1
]}

Samanta, Supravat ^{[1
]}

Mohan, Darapaneni Chandra ^{[1
]}

Reddy, N. Naresh Kumar ^{[1
]}

Adimurthy, Subbarayappa ^{[1
]}

机构：

[1] Cent Salt & Marine Chem Res Inst, CSIR, Acad Sci & Innovat Res, GB Marg, Bhavnagar 364002, Gujarat, India

来源：

SYNTHESIS-STUTTGART | 2017年 / 49卷 / 11期

关键词：

N-methylpyrrolidone; chalcones; metal-free; drug intermediates; 3+2] cycloaddition; DOPAMINE-RECEPTOR BINDING; 3+2 CYCLOADDITION; DERIVATIVES; YLIDES; CYCLIZATION; HETEROCYCLES; PYRAZOLES; EFFICACY;

D O I：

10.1055/s-0036-1588753

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of functionalized pyrazolo[1,5-a]pyridines through oxidative [3+2] cycloaddition of N-aminopyridines with alpha,beta-unsaturated carbonyl compounds or electron-withdrawing olefins is described. The reactions proceed in N-methylpyrrolidone as the solvent under metal-free conditions at room temperature.

引用

页码：2513 / 2522

页数：10

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