Microrheology with Optical Tweezers: Measuring the relative viscosity of solutions 'at a glance'

被引：59

作者：

Tassieri, Manlio ^{[1
]}

Del Giudice, Francesco ^{[2
]}

Robertson, Emma J. ^{[3
]}

Jain, Neena ^{[4
]}

Fries, Bettina ^{[4
]}

Wilson, Rab ^{[1
]}

Glidle, Andrew ^{[1
]}

Greco, Francesco ^{[5
]}

Netti, Paolo Antonio ^{[2
]}

Maffettone, Pier Luca ^{[6
]}

Bicanic, Tihana ^{[3
]}

Cooper, Jonathan M. ^{[1
]}

机构：

[1] Univ Glasgow, Sch Engn, Div Biomed Engn, Glasgow G12 8LT, Lanark, Scotland

[2] IIT, Ctr Adv Biomat Hlth Care CRIB, I-80125 Naples, Italy

[3] St Georges Univ London, Dept Infect & Immun, London SW17 0RS, England

[4] Albert Einstein Coll Med, Dept Med, Bronx, NY 10467 USA

[5] IRC CNR, Ist Ric Combust, I-80125 Naples, Italy

[6] Univ Naples Federico II, Dipartimento Ingn Chim Mat & Prod Ind, I-80125 Naples, Italy

来源：

SCIENTIFIC REPORTS | 2015年 / 5卷

基金：

英国工程与自然科学研究理事会; 英国惠康基金;

关键词：

ROD-LIKE MACROMOLECULES; VISCOELASTIC MODULI; DYNAMICS; SUSPENSIONS; VISCOMETER; SCATTERING; RHEOLOGY;

D O I：

10.1038/srep08831

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We present a straightforward method for measuring the relative viscosity of fluids via a simple graphical analysis of the normalised position autocorrelation function of an optically trapped bead, without the need of embarking on laborious calculations. The advantages of the proposed microrheology method are evident when it is adopted for measurements of materials whose availability is limited, such as those involved in biological studies. The method has been validated by direct comparison with conventional bulk rheology methods, and has been applied both to characterise synthetic linear polyelectrolytes solutions and to study biomedical samples.

引用

页数：6

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