Cationic corrole derivatives: a new family of G-quadruplex inducing and stabilizing ligands

被引:87
作者
Fu, Boqiao
Huang, Jing
Ren, Lige
Weng, Xiaocheng
Zhou, Yangyang
Du, Yuhao
Wu, Xiaojun
Zhou, Xiang [1 ]
Yang, Guangfu
机构
[1] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China
[2] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China
关键词
D O I
10.1039/b704599a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Water-soluble cationic corrole derivatives were designed and synthesized, and the first observation of their interactions with the telomeric G-quadruplex was made.
引用
收藏
页码:3264 / 3266
页数:3
相关论文
共 35 条
  • [1] AVIEZER D, 2000, CANCER RES, V60, P2073
  • [2] HAIRPIN AND PARALLEL QUARTET STRUCTURES FOR TELOMERIC SEQUENCES
    BALAGURUMOORTHY, P
    BRAHMACHARI, SK
    MOHANTY, D
    BANSAL, M
    SASISEKHARAN, V
    [J]. NUCLEIC ACIDS RESEARCH, 1992, 20 (15) : 4061 - 4067
  • [3] Switching and signaling at the telomere
    Blackburn, EH
    [J]. CELL, 2001, 106 (06) : 661 - 673
  • [4] Beginning to understand the end of the chromosome
    Cech, TR
    [J]. CELL, 2004, 116 (02) : 273 - 279
  • [5] 5,10,15-tris(o-aminophenyl) corrole (TAPC) as a versatile synthon for the preparation of corrole-based hemoprotein analogs
    Collman, JP
    Decréau, RA
    [J]. ORGANIC LETTERS, 2005, 7 (06) : 975 - 978
  • [6] Porphyrin derivatives for telomere binding and telomerase inhibition
    Dixon, IM
    Lopez, F
    Estève, JP
    Tejera, AM
    Blasco, MA
    Pratviel, G
    Meunier, B
    [J]. CHEMBIOCHEM, 2005, 6 (01) : 123 - 132
  • [7] A G-quadruplex ligand with 10000-fold selectivity over duplex DNA
    Dixon, Isabelle M.
    Lopez, Frederic
    Tejera, Agueda M.
    Esteve, Jean-Pierre
    Blasco, Maria A.
    Pratviel, Genevieve
    Meunier, Bernard
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (06) : 1502 - +
  • [8] Telomerase: a potential therapeutic target for cancer
    Fletcher, TM
    [J]. EXPERT OPINION ON THERAPEUTIC TARGETS, 2005, 9 (03) : 457 - 469
  • [9] PROMOTION OF PARALLEL DNA QUADRUPLEXES BY A YEAST TELOMERE BINDING-PROTEIN - A CIRCULAR-DICHROISM STUDY
    GIRALDO, R
    SUZUKI, M
    CHAPMAN, L
    RHODES, D
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (16) : 7658 - 7662
  • [10] Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins
    Goncalves, Diana P. N.
    Ladame, Sylvain
    Balasubramanian, Shankar
    Sanders, Jeremy K. M.
    [J]. ORGANIC & BIOMOLECULAR CHEMISTRY, 2006, 4 (17) : 3337 - 3342