Peripheral T-cell Lymphomas: Updates in Allogeneic Hematopoietic Stem Cell Transplantation

被引:3
作者
Huang, Wen-Rong [1 ]
Liu, Dai-Hong [1 ]
机构
[1] Chinese Peoples Liberat Army Gen Hosp, Dept Hematol, Beijing 100853, Peoples R China
关键词
Allogeneic; Hematopoietic Stem Cell Transplantation; Peripheral T-cell Lymphoma; Survival; NON-HODGKIN-LYMPHOMA; MARROW TRANSPLANTATION; WORKING PARTY; SINGLE-CENTER; RELAPSE; SURVIVAL; BLOOD; EXPERIENCE; OUTCOMES; REGISTRY;
D O I
10.4103/0366-6999.239315
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: Peripheral T-cell lymphomas (PTCLs) confer dismal prognosis and no consensus has been established on the role of allogeneic hematopoietic stem cell transplantation (allo-HSCT) due to its rarity and heterogeneity. The purpose was to review key points of allo-HSCT for PTCLs, including indication, times of transplantation, conditioning regimen, graft versus host disease prophylaxis, and treatment of relapse. Data Sources: A comprehensive search in PubMed and Cochrane up to February 28, 2018, with the keywords "Peripheral", "T", "Lymphoma", and "Transplantation" was done. Study Selection: Relevant articles including HSCT for PTCLs were carefully reviewed. Results: Promising data have been reported from advances in transplant technology and more and more PTCLs patients with poor prognosis could benefit from allo-HSCT. Conclusion: Allo-HSCT is a useful choice for patients with refiactory/relapsed PTCLs or high-risk new diagnosed PTCLs.
引用
收藏
页码:2105 / +
页数:8
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