Instant Clue: A Software Suite for Interactive Data Visualization and Analysis

被引:172
作者
Nolte, Hendrik [1 ,2 ]
MacVicar, Thomas D. [1 ,2 ]
Tellkamp, Frederik [1 ,2 ,3 ,4 ]
Krueger, Marcus [1 ,2 ,4 ]
机构
[1] Univ Cologne, Inst Genet, Joseph Stelzmann Str 26, D-50931 Cologne, Germany
[2] Univ Cologne, Cologne Excellence Cluster Cellular Stress Respon, Joseph Stelzmann Str 26, D-50931 Cologne, Germany
[3] Univ Cologne, Ctr Mol Med Cologne, Dept Dermatol, D-50931 Cologne, Germany
[4] Univ Cologne, Ctr Mol Med CMMC, D-50931 Cologne, Germany
关键词
PHOSPHOPROTEOME REVEALS; QUANTITATIVE-ANALYSIS; TOOL; MITOCHONDRIA; SYSTEM; PARL;
D O I
10.1038/s41598-018-31154-6
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The development of modern high-throughput instrumentation and improved core facility infrastructures leads to an accumulation of large amounts of scientific data. However, for a majority of scientists the comprehensive analysis and visualization of their data goes beyond their expertise. To reduce this hurdle, we developed a software suite called Instant Clue that helps scientists to visually analyze data and to gain insights into biological processes from their high-dimensional dataset. Instant Clue combines the power of visual and statistical analytics using a straight forward drag & drop approach making the software highly intuitive. Additionally, it offers a comprehensive portfolio of statistical tools for systematic analysis such as dimensional reduction, (un)-supervised learning, clustering, multi-block (omics) integration and curve fitting. Charts can be combined with high flexibility into a main figure template for direct usage in scientific publications. Even though Instant Clue was developed with the omics-sciences in mind, users can analyze any kind of data from low to high dimensional data sets. The open-source software is available for Windows and Mac OS (http://www.instantclue.uni-koeln.de) and is accompanied by a detailed video tutorial series.
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页数:8
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