Gastric myeloid sarcoma without acute myeloblastic leukemia

被引:14
作者
Huang, Xiao-Li [1 ]
Tao, Jin [1 ]
Li, Jian-Zhong [1 ]
Chen, Xiao-Liang [1 ]
Chen, Jian-Ning [2 ]
Shao, Chun-Kui [2 ]
Wu, Bin [1 ]
机构
[1] Sun Yat Sen Univ, Affiliated Hosp 3, Dept Gastroenterol, Guangzhou 510630, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Affiliated Hosp 3, Dept Pathol, Guangzhou 510630, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
Myeloid sarcoma; Stomach; Acute myeloblastic leukemia; Abdominal pain; Immunohistochemistry; GRANULOCYTIC-SARCOMA; TUMORS;
D O I
10.3748/wjg.v21.i7.2242
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Myeloid sarcomas (MS) involve extramedullary blast proliferation from one or more myeloid lineages that replace the original tissue architecture, and these neoplasias are called granulocytic sarcomas, chloromas or extramedullary myeloid tumors. Such tumors develop in lymphoid organs, bones (e.g., skulls and orbits), skin, soft tissue, various mucosae, organs, and the central nervous system. Gastrointestinal (GI) involvement is rare, while the occurrence of myeloid sarcomas in patients without leukemia is even rare. Here, we report a case of a 38-year-old man who presented with epigastric pain and progressive jaundice. An upper GI endoscopy had shown extensive multifocal hyperemic fold thickening and the spread of nodular lesions in the body of the stomach. Biopsies from the gastric lesions indicated myeloid sarcoma of the stomach. However, concurrent peripheral blood and bone marrow examinations showed no evidence of acute myeloid leukemia. For diagnosis, the immunohistochemical markers must be checked when evaluating a suspected myeloid sarcoma case. Accurate MS diagnosis determines the appropriate therapy and prognosis.
引用
收藏
页码:2242 / 2248
页数:7
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