The Odyssey of Bioactive Compounds in Avocado (Persea americana) and Their Health Benefits

被引:138
作者
Bhuyan, Deep Jyoti [1 ]
Alsherbiny, Muhammad A. [1 ,2 ]
Perera, Saumya [1 ]
Low, Mitchell [1 ]
Basu, Amrita [3 ]
Devi, Okram Abemsana [4 ]
Barooah, Mridula Saikia [4 ]
Li, Chun Guang [1 ]
Papoutsis, Konstantinos [5 ]
机构
[1] Western Sydney Univ, NICM Hlth Res Inst, Penrith, NSW 2751, Australia
[2] Cairo Univ, Fac Pharm, Dept Pharmacognosy, Cairo 11562, Egypt
[3] Masaryk Univ, Res Ctr Tox Cpds Environm, Brno 62500, Czech Republic
[4] Assam Agr Univ, Coll Community Sci, Dept Food Sci & Nutr, Jorhat 785013, Assam, India
[5] Univ Coll Dublin, Sch Agr & Food Sci, Dublin 4, Ireland
关键词
avocado; Persea americana; metabolites; antioxidants; anticancer; antimicrobial; anti-inflammatory; diabetes; cardiovascular diseases (CVD); bioavailability and pharmacokinetic; PROSTAGLANDIN E-2 PRODUCTION; IN-VITRO EVALUATION; ANTIOXIDANT ACTIVITY; HUMAN BREAST; HASS AVOCADO; AVOCADO/SOYBEAN UNSAPONIFIABLES; SOYBEAN UNSAPONIFIABLES; NITRIC-OXIDE; DOUBLE-BLIND; VITAMIN-A;
D O I
10.3390/antiox8100426
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Persea americana, commonly known as avocado, has recently gained substantial popularity and is often marketed as a "superfood" because of its unique nutritional composition, antioxidant content, and biochemical profile. However, the term "superfood" can be vague and misleading, as it is often associated with unrealistic health claims. This review draws a comprehensive summary and assessment of research performed in the last few decades to understand the nutritional and therapeutic properties of avocado and its bioactive compounds. In particular, studies reporting the major metabolites of avocado, their antioxidant as well as bioavailability and pharmacokinetic properties, are summarized and assessed. Furthermore, the potential of avocado in novel drug discovery for the prevention and treatment of cancer, microbial, inflammatory, diabetes, and cardiovascular diseases is highlighted. This review also proposes several interesting future directions for avocado research.
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页数:53
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